Infertile woman gives birth after ’boost’ to ovaries
2013 09 30

By Linda Geddes | NewScientist

A baby boy has been born following a new fertility treatment that awakens dormant eggs in women who have stopped menstruating.

The treatment could help women who have left child-bearing too late, or have been left infertile after treatment for cancer. But some have raised concerns that the technique has been rushed to the clinic before being properly tested.

Women are born with millions of immature eggs, or follicles, but only around 400 mature to the point where an egg is released into the fallopian tubes and could be fertilised. But some of these follicles remain, even after a woman has stopped menstruating.

Now researchers have found a way to wake these dormant follicles and produce eggs that are capable of being fertilised. The first test of this technique has resulted in a baby boy, born in December 2012 in Japan.

Immature follicles are usually kept in a dormant state by the PTEN gene, which suppresses a signalling pathway involved in cell growth. Aaron Hsueh at Stanford University Medical School in California and his colleagues had previously showed that immature mouse follicles could be stimulated to mature if pieces of ovary were incubated with a molecule that stimulates the signalling pathway that PTEN inhibits.

Hsueh’s team also discovered that the physical act of cutting up the ovaries disrupts a second signalling pathway, called the Hippo pathway, which normally suppresses the growth of many of the body’s other organs as well.

[...]

Read the full article at: newscientist.com




READ: Making Babies After Death: It’s Possible, But Is It Ethical?






Related Articles
Oh Baby! Man ’Fathered 600 Children’ at Own Fertility Clinic
One Sperm Donor with 150 Sons and Daughters
Court says widow can use dead husband’s sperm
Woman set to give birth from her own mother’s womb after world-first transplant
What are a Surrogate’s Rights or Responsibilities? Woman’s Controversial Pregnancy in Spotlight
‘Super-surrogate’ Meredith Olafson retires uterus after 15th baby
India seeks to regulate its booming ’rent-a-womb’ industry


Latest News from our Front Page

US Silent on Psychologists Role in CIA’s Tortures: Doctors
2014-12-20 21:53
Physicians for Human Rights had not received any response from the US Federal Commission to their call to investigate the role of health professionals in CIA’s torture program, Deputy Director of the organization told Sputnik. December 19 (Sputnik) — US government has not responded to calls to prosecute doctors, who participated in CIA torture program, the Deputy Director of Communications for ...
Ziolebrities: Simon Cowell donates £100,000 to Israeli soldiers to please pregnant jewish girlfriend Lauren Silverman
2014-12-20 21:00
Cowell, 54, is also planning a secret trip to Israel soon as he embraces the Jewish faith of Silverman, 36 Gala: Billionaire Haim Saban with Cowell Simon Cowell has publicly donated nearly £100,000 in support of the Israeli army. The X Factor boss pledged the cash to the Friends of the Israel Defense Forces at a US fund-raiser in Beverly Hills. The lavish gala ...
Former Chief Security Officer for NewsCorp: N. Koreans Not Behind Sony Hack, Interview Leak
2014-12-20 2:17
Hemanshu Nigam, a former federal prosecutor and former chief security officer for NewsCorp/Fox studios, says North Korea isn’t behind the Sony Hack. Nigam gave several bullet points for why the hack was likely an inside job. Attack code borrowed from a previous attack on Seoul, that’s why it’s in Korean. Private hackers typically borrow malicious code from other hackers.Nations state attacks follow ...
Sony Fires Back at Obama: Actually We Did Call the White House – Several Times
2014-12-20 2:13
Sony fired back at Obama after the press conference saying they had several conversations with the Obama White House before and after the movie was canceled. Via The Hollywood Reporter: After President Obama criticized Sony for its decision to cancel The Interview's release after theater chains decided not to show the film, the studio has issued a statement elaborating on the move. “The ...
The Bankster International
2014-12-20 1:55
Geopolitical analysis, the art of explaining power relationships through the prism of impersonal geography, can be a helpful tool for observers of the Great Game – but it also has its limitations. A case in point is the renewed US-Russia confrontation. Think tanks and policy insiders easily sell the narrative that from the dark days of the Cold War to ...
More News »