Infertile woman gives birth after ’boost’ to ovaries
2013-09-30 0:00

By Linda Geddes | NewScientist

A baby boy has been born following a new fertility treatment that awakens dormant eggs in women who have stopped menstruating.

The treatment could help women who have left child-bearing too late, or have been left infertile after treatment for cancer. But some have raised concerns that the technique has been rushed to the clinic before being properly tested.

Women are born with millions of immature eggs, or follicles, but only around 400 mature to the point where an egg is released into the fallopian tubes and could be fertilised. But some of these follicles remain, even after a woman has stopped menstruating.

Now researchers have found a way to wake these dormant follicles and produce eggs that are capable of being fertilised. The first test of this technique has resulted in a baby boy, born in December 2012 in Japan.

Immature follicles are usually kept in a dormant state by the PTEN gene, which suppresses a signalling pathway involved in cell growth. Aaron Hsueh at Stanford University Medical School in California and his colleagues had previously showed that immature mouse follicles could be stimulated to mature if pieces of ovary were incubated with a molecule that stimulates the signalling pathway that PTEN inhibits.

Hsueh’s team also discovered that the physical act of cutting up the ovaries disrupts a second signalling pathway, called the Hippo pathway, which normally suppresses the growth of many of the body’s other organs as well.


Read the full article at:

READ: Making Babies After Death: It’s Possible, But Is It Ethical?

Related Articles
Oh Baby! Man ’Fathered 600 Children’ at Own Fertility Clinic
One Sperm Donor with 150 Sons and Daughters
Court says widow can use dead husband’s sperm
Woman set to give birth from her own mother’s womb after world-first transplant
What are a Surrogate’s Rights or Responsibilities? Woman’s Controversial Pregnancy in Spotlight
‘Super-surrogate’ Meredith Olafson retires uterus after 15th baby
India seeks to regulate its booming ’rent-a-womb’ industry

Latest News from our Front Page

Sweden to give over 8 million euros to Turkey for "refugee deal" - Europe to give three billion euros total
2015-12-01 1:44
Prime Minister Stefan Löfven announced on Sunday that Sweden would contribute to a joint action plan agreed by nine EU nations designed to limit the number of refugees arriving in Europe via Turkey. The deal came after the German Chancellor Angela Merkel held a surprise summit in Brussels involving the leaders of nine countries including Sweden, France and the UK. The European ...
Swedish woman raped by "refugee" refuses to report it because she feels sorry for him
2015-12-01 0:12
Victim sympathized with rapist's "difficult situation" A Swedish woman who was raped by an Iraqi “refugee” on a train initially refused to report the incident to police because she ‘felt sorry’ for her attacker. The incident occurred on a night train between UmeĂ„ and Sundsvall back in October. The Iraqi refugee was traveling back to Sweden because he was unhappy with the ...
ISIS Oil Trade Full Frontal: "Raqqa's Rockefellers," Bilal Erdogan, KRG Crude, And The Israel Connection
2015-11-30 21:56
"Effectively, we have been financially discriminated against for a long time. By early 2014, when we did not receive the budget, we decided we need to start thinking about independent oil sales” --  Ashti Hawrami, Kurdistan’s minister for natural resources In June of 2014, the SCF Altai (an oil tanker) arrived at Ashkelon port. Hours later, the first shipment of Kurdish ...
Prosecutors ban Soros Foundation as 'threat to Russian national security'
2015-11-30 21:04
The Russian Prosecutor General’s Office has recognized George Soros’s Open Society Institute and another affiliated organization as undesirable groups, banning Russian citizens and organizations from participation in any of their projects. In a statement released on Monday, prosecutors said the activities of the Open Society Institute and the Open Society Institute Assistance Foundation were a threat to the foundations of Russia’s ...
Israeli Colonel Caught with Islamic State (IS) Pants Down
2015-11-30 21:11
This was definitely not supposed to happen. It seems that an Israeli military man with the rank of colonel was “caught with IS pants down.” By that I mean he was captured amid a gaggle of so-called IS–or Islamic State or ISIS or DAESH depending on your preference–terrorists, by soldiers of the Iraqi army. Under interrogation by the Iraqi intelligence ...
More News »