Infertile woman gives birth after ’boost’ to ovaries
2013 09 30

By Linda Geddes | NewScientist

A baby boy has been born following a new fertility treatment that awakens dormant eggs in women who have stopped menstruating.

The treatment could help women who have left child-bearing too late, or have been left infertile after treatment for cancer. But some have raised concerns that the technique has been rushed to the clinic before being properly tested.

Women are born with millions of immature eggs, or follicles, but only around 400 mature to the point where an egg is released into the fallopian tubes and could be fertilised. But some of these follicles remain, even after a woman has stopped menstruating.

Now researchers have found a way to wake these dormant follicles and produce eggs that are capable of being fertilised. The first test of this technique has resulted in a baby boy, born in December 2012 in Japan.

Immature follicles are usually kept in a dormant state by the PTEN gene, which suppresses a signalling pathway involved in cell growth. Aaron Hsueh at Stanford University Medical School in California and his colleagues had previously showed that immature mouse follicles could be stimulated to mature if pieces of ovary were incubated with a molecule that stimulates the signalling pathway that PTEN inhibits.

Hsueh’s team also discovered that the physical act of cutting up the ovaries disrupts a second signalling pathway, called the Hippo pathway, which normally suppresses the growth of many of the body’s other organs as well.

[...]

Read the full article at: newscientist.com




READ: Making Babies After Death: It’s Possible, But Is It Ethical?






Related Articles
Oh Baby! Man ’Fathered 600 Children’ at Own Fertility Clinic
One Sperm Donor with 150 Sons and Daughters
Court says widow can use dead husband’s sperm
Woman set to give birth from her own mother’s womb after world-first transplant
What are a Surrogate’s Rights or Responsibilities? Woman’s Controversial Pregnancy in Spotlight
‘Super-surrogate’ Meredith Olafson retires uterus after 15th baby
India seeks to regulate its booming ’rent-a-womb’ industry


Latest News from our Front Page

Sand Pirates: ISIS Are America’s 21st Century Terrorist Privateers
2014 11 01
What is ISIS? If you believe govt and corporate propaganda, you still think that ISIS is a grassroots Islamic ideological movement ¨C and with no connection to intelligence agencies like America¡¯s CIA, Britain¡¯s MI6, Turkish (NATO) intelligence, Saudi intelligence, Israeli intelligence, or Pakistan¡¯s ISI. The reality of ISIS is something altogether different¡­ On closer inspection, these marauding paramilitary ISIS gangs are nothing ...
Ancient Stone Circles in Mideast Baffle Archaeologists
2014 11 01
Huge stone circles in the Middle East have been imaged from above, revealing details of structures that have been shrouded in mystery for decades. The Big Circle called J1 is about 390 meters (1,280 feet) in diameter, with an open area created by bulldozing in its interior. Credit: David L. Kennedy, copyright is retained by the Aerial Photographic Archive for Archaeology ...
Sweden Recognizes Palestinian State; Israel Upset
2014 10 31
Sweden on Thursday became the biggest Western European country to recognize a Palestinian state, prompting a strong protest from Israel, which swiftly withdrew its ambassador from Stockholm. The move by Sweden’s new left-leaning government reflects growing international impatience with Israel’s nearly half-century control of the West Bank, east Jerusalem and its blockade of the Gaza Strip. It also comes during increased ...
Fed-Backed Study: How to Brainwash Public into Fearing “Climate Change” Like Ebola
2014 10 31
$84K study seeks ways to make public fear "climate change and overpopulation" The National Science Foundation is funding a study to determine how to brainwash the public into fearing “climate change and overpopulation” as if they were Ebola. The NSF awarded an $84,000 grant to researchers at the State University of New York at Buffalo yesterday to figure out how to make ...
Brain decoder can eavesdrop on your inner voice
2014 10 31
As you read this, your neurons are firing – that brain activity can now be decoded to reveal the silent words in your head TALKING to yourself used to be a strictly private pastime. That’s no longer the case – researchers have eavesdropped on our internal monologue for the first time. The achievement is a step towards helping people who cannot ...
More News »