Infertile woman gives birth after ’boost’ to ovaries
2013 09 30

By Linda Geddes | NewScientist

A baby boy has been born following a new fertility treatment that awakens dormant eggs in women who have stopped menstruating.

The treatment could help women who have left child-bearing too late, or have been left infertile after treatment for cancer. But some have raised concerns that the technique has been rushed to the clinic before being properly tested.

Women are born with millions of immature eggs, or follicles, but only around 400 mature to the point where an egg is released into the fallopian tubes and could be fertilised. But some of these follicles remain, even after a woman has stopped menstruating.

Now researchers have found a way to wake these dormant follicles and produce eggs that are capable of being fertilised. The first test of this technique has resulted in a baby boy, born in December 2012 in Japan.

Immature follicles are usually kept in a dormant state by the PTEN gene, which suppresses a signalling pathway involved in cell growth. Aaron Hsueh at Stanford University Medical School in California and his colleagues had previously showed that immature mouse follicles could be stimulated to mature if pieces of ovary were incubated with a molecule that stimulates the signalling pathway that PTEN inhibits.

Hsueh’s team also discovered that the physical act of cutting up the ovaries disrupts a second signalling pathway, called the Hippo pathway, which normally suppresses the growth of many of the body’s other organs as well.

[...]

Read the full article at: newscientist.com




READ: Making Babies After Death: It’s Possible, But Is It Ethical?






Related Articles
Oh Baby! Man ’Fathered 600 Children’ at Own Fertility Clinic
One Sperm Donor with 150 Sons and Daughters
Court says widow can use dead husband’s sperm
Woman set to give birth from her own mother’s womb after world-first transplant
What are a Surrogate’s Rights or Responsibilities? Woman’s Controversial Pregnancy in Spotlight
‘Super-surrogate’ Meredith Olafson retires uterus after 15th baby
India seeks to regulate its booming ’rent-a-womb’ industry


Latest News from our Front Page

Document Confirms British were Plotting to Invade Germay Before Germany Invaded Poland
2014 09 02
The declaration of war against Germany had nothing to do with Poland, and was in fact a brutal war of aggression launched for economic reasons against the peaceful German people. As you can see in Judea Declares War on Germany. From dailymail.co.uk: An early version of the ‘King’s Speech’ reveals Britain was preparing to declare war on Germany before Hitler invaded ...
Study Claims Cave Art Made by Neanderthals
2014 09 02
A series of lines scratched into rock in a cave near the southwestern tip of Europe could be proof that Neanderthals were more intelligent and creative than previously thought. The cross-hatched engravings inside Gorham’s Cave in Gibraltar are the first known examples of Neanderthal rock art, according to a team of scientists who studied the site. The find is significant because ...
EU Nanny State to Ban Toasters, Kettles & Hair Dryers!
2014 09 02
"Despite arctic sea ice growing by 43%, the EU nanny state is set to ban toasters, hair dryers and kettles in the name of preventing global warming."
Nigeria launches new biometric ID card - brought to you by Mastercard
2014 09 02
Yesterday afternoon, president Goodluck Jonathan became the first recipient of Nigeria’s new national eID card, in a ceremony at the presidential villa in the capital Abuja. The cards will be issued to 13 million Nigerians as part of a pilot project, with the ultimate aim of producing a national identity management system (NIMS). Nigeria’s NIMS is an ambitious attempt to consolidate ...
LA Times Now Describing Illegal Aliens As ’Informal Workers’ Who ’Labor Unofficially’
2014 09 02
Via Weasel Zippers, we learned the Los Angeles Times has a new term for illegal aliens in the work force: they’re “informal workers,” and that doesn’t mean they don’t arrive on the job in a tuxedo. Times reporter Tiffany Hsu (a "UC Berkeley grad") began her Saturday story with the new I-word (and illegal immigrants also “labored unofficially” in "gray employment"): Informal ...
More News »