Basically, she outlined the problems with the euro perfectly, that Germany would chafe at the inevitable need for greater inflation, and that the poorer countries would inevitably be uncompetitive and need bailouts that would not easily be forthcoming.
This paragraph is from "The Path To Power," where she discusses conversations with John Major (her successor) about negotiating with the rest of Europe. She just totally nails the inflation and competitiveness angles.
Watch Margaret Thatcher Explain Why the Euro Is a Terrible Idea in 1990
By Jordan Weissmann | TheAtlantic
Say what you will about the rest of her legacy, but when it comes to the economic disaster today known as the euro, Margaret Thatcher was downright prophetic. In a delightfully acidic speech delivered before Britain’s House of Commons in 1990, and posted below, she summed up her feelings about European integration: "No. No. No."
Specifically, Thatcher opposed to the idea of handing political power to a European parliament, giving up the pound for a single European currency, or handing over its monetary policy to a European central bank. As she put it (in the blunt way only British politicians can):
Perhaps the Labour party would give all those things up easily. Perhaps it would agree to a single currency and abolition of the pound sterling. Perhaps, being totally incompetent in monetary matters, it would be only too delighted to hand over full responsibility to a central bank, as it did to the IMF. The fact is that the Labour party has no competence on money and no competence on the economy -- so, yes, the right hon. Gentleman would be glad to hand it all over. What is the point of trying to get elected to Parliament only to hand over sterling and the powers of this House to Europe?
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Last December, an unsettling Nature Neuroscience study found that mice who were taught to associate the smell of cherry blossoms with pain produced offspring who feared the smell of cherry blossoms, even if they had never been exposed to it before. We knew that the process was epigenetic—that it was not hard-wired in the permanent genetic structure of the mouse—but ...