Scientists reprogram body’s own cells to kill cancer, HIV
2013 03 26

By David Gutierrez | Natural News

In a pair of papers published in the journal Cell Stem Cell, researchers from two separate Japanese universities have successfully used a new technique to reprogram the body’s own immune cells to seek out and destroy cancer cells and HIV. The researchers hope that this technique can be developed into a practical therapy for cancer, HIV and other hard-to-treat conditions. Ideally such a therapy would be free of side effects, as it would make use of the body’s own innate immune capability.

The body naturally produces a type of immune cell, killer T lymphocytes, that possesses the ability to kill not only viral and bacterial invaders, but also to destroy certain compromised cells of the body itself, such as cancerous cells or those infected with the herpes virus. Unfortunately, killer T lymphocytes are normally very short-lived, and often fail to destroy tumors before expiring themselves (this explains why, in spite of our immune systems, we still sometimes develop cancer). Experimental therapies seeking to use the body’s own T lymphocytes to fight cancer have also often failed due to the cells’ short lifespan.

In the new studies, researchers used a group of compounds known as "Yamanaka factors," which cause cells to revert into their earlier, undifferentiated stem cell form. These stem cells are of a variety known as induced pluripotent stem cells (iPS cells), with "pluripotent" meaning that the stem cells are able to differentiate into more than one type of cell.

The researchers then allowed the iPS cells to re-differentiate back into killler T lymphocytes. They found that this "reboot" produced killer T lympocytes with much longer lifespans.

Rebooting the killer T cells

In one study, researchers from the RIKEN Research Centre for Allergy and Immunology created iPS cells from killer T lymphocytes that had developed to target melanoma skin tumors. The iPS cells then differentiated back into T lymphocytes that, strikingly, were not only able to recognize the MART-1 protein characteristic of melanoma and to produce to the anti-tumor chemical interferon ?, but also were much longer-lived than natural T lymphocytes, and remained active as anti-cancer agents for their entire extended lifespan.

[...]

Read the full article at: naturalnews.com



Related Articles
Why can’t doctors tell cancer patients the truth?
EU Releases All Data on GM Corn Linked to Cancer
Cancer cells are dormant during chemotherapy
In breakthrough, patients’ immune systems attack cancer cells


Latest News from our Front Page

If Someone Secretly Controlled What You Say, Would Anyone Notice?
2014 10 01
The subject enters a room in which a 12-year-old boy is seated. A 20-minute conversation ensues. The subject quizzes the boy about current events and other topics to get a sense of his intelligence and personality. But the boy is not what he appears to be. Unbeknownst to the subject, the boy is wearing a radio receiver in his ear, and ...
Obama has had accurate intelligence about ISIS since BEFORE the 2012 election, says administration insider
2014 10 01
‘President Barack Obama’s intelligence briefings have provided him with specific information since before he won re-election in 2012 about the growing threat of the terror group now known alternatively as ISIS and ISIL, an administration insider told MailOnline on Monday. ‘Unless someone very senior has been shredding the president’s daily briefings and telling him that the dog ate them, highly accurate ...
Can holding a magnet against your head help defeat depression?
2014 10 01
Former GP Sue Mildred suffered from crippling depression and anxiety for 20 years. On two occasions it was so severe that she ended up in hospital, and for 15 years she was unable to work. Sue, 51, has tried antidepressants, talking therapies and, out of desperation, even ECT (electro-convulsive therapy), where an electric current is passed through the brain. This did ...
Extremists to have Facebook and Twitter vetted by anti-terror police
2014 09 30
Theresa May to announce new Extremist Disruption Orders to strengthen counter-terrorism if the Tories win the next general election Extremists will have to get posts on Facebook and Twitter approved in advance by the police under sweeping rules planned by the Conservatives. They will also be barred from speaking at public events if they represent a threat to “the functioning of democracy”, ...
Scottish Independence: Protesters demand revote
2014 09 30
Pro-independence campaigners gathered outside the Scottish Parliament for the second day in a row, this time to demand a revote of the September 18 referendum. While yesterday’s “Rally For A Revote” saw the return of Saltires and Yes banners to Holyrood, it did not match the turnout for the “Voice Of The People” rally held on Saturday, when up 3000 people ...
More News »