Scientists reprogram body’s own cells to kill cancer, HIV
2013 03 26

By David Gutierrez | Natural News

In a pair of papers published in the journal Cell Stem Cell, researchers from two separate Japanese universities have successfully used a new technique to reprogram the body’s own immune cells to seek out and destroy cancer cells and HIV. The researchers hope that this technique can be developed into a practical therapy for cancer, HIV and other hard-to-treat conditions. Ideally such a therapy would be free of side effects, as it would make use of the body’s own innate immune capability.

The body naturally produces a type of immune cell, killer T lymphocytes, that possesses the ability to kill not only viral and bacterial invaders, but also to destroy certain compromised cells of the body itself, such as cancerous cells or those infected with the herpes virus. Unfortunately, killer T lymphocytes are normally very short-lived, and often fail to destroy tumors before expiring themselves (this explains why, in spite of our immune systems, we still sometimes develop cancer). Experimental therapies seeking to use the body’s own T lymphocytes to fight cancer have also often failed due to the cells’ short lifespan.

In the new studies, researchers used a group of compounds known as "Yamanaka factors," which cause cells to revert into their earlier, undifferentiated stem cell form. These stem cells are of a variety known as induced pluripotent stem cells (iPS cells), with "pluripotent" meaning that the stem cells are able to differentiate into more than one type of cell.

The researchers then allowed the iPS cells to re-differentiate back into killler T lymphocytes. They found that this "reboot" produced killer T lympocytes with much longer lifespans.

Rebooting the killer T cells

In one study, researchers from the RIKEN Research Centre for Allergy and Immunology created iPS cells from killer T lymphocytes that had developed to target melanoma skin tumors. The iPS cells then differentiated back into T lymphocytes that, strikingly, were not only able to recognize the MART-1 protein characteristic of melanoma and to produce to the anti-tumor chemical interferon ?, but also were much longer-lived than natural T lymphocytes, and remained active as anti-cancer agents for their entire extended lifespan.

[...]

Read the full article at: naturalnews.com



Related Articles
Why can’t doctors tell cancer patients the truth?
EU Releases All Data on GM Corn Linked to Cancer
Cancer cells are dormant during chemotherapy
In breakthrough, patients’ immune systems attack cancer cells


Latest News from our Front Page

US Silent on Psychologists Role in CIA’s Tortures: Doctors
2014-12-20 21:53
Physicians for Human Rights had not received any response from the US Federal Commission to their call to investigate the role of health professionals in CIA’s torture program, Deputy Director of the organization told Sputnik. December 19 (Sputnik) — US government has not responded to calls to prosecute doctors, who participated in CIA torture program, the Deputy Director of Communications for ...
Ziolebrities: Simon Cowell donates £100,000 to Israeli soldiers to please pregnant jewish girlfriend Lauren Silverman
2014-12-20 21:00
Cowell, 54, is also planning a secret trip to Israel soon as he embraces the Jewish faith of Silverman, 36 Gala: Billionaire Haim Saban with Cowell Simon Cowell has publicly donated nearly £100,000 in support of the Israeli army. The X Factor boss pledged the cash to the Friends of the Israel Defense Forces at a US fund-raiser in Beverly Hills. The lavish gala ...
Former Chief Security Officer for NewsCorp: N. Koreans Not Behind Sony Hack, Interview Leak
2014-12-20 2:17
Hemanshu Nigam, a former federal prosecutor and former chief security officer for NewsCorp/Fox studios, says North Korea isn’t behind the Sony Hack. Nigam gave several bullet points for why the hack was likely an inside job. Attack code borrowed from a previous attack on Seoul, that’s why it’s in Korean. Private hackers typically borrow malicious code from other hackers.Nations state attacks follow ...
Sony Fires Back at Obama: Actually We Did Call the White House – Several Times
2014-12-20 2:13
Sony fired back at Obama after the press conference saying they had several conversations with the Obama White House before and after the movie was canceled. Via The Hollywood Reporter: After President Obama criticized Sony for its decision to cancel The Interview's release after theater chains decided not to show the film, the studio has issued a statement elaborating on the move. “The ...
The Bankster International
2014-12-20 1:55
Geopolitical analysis, the art of explaining power relationships through the prism of impersonal geography, can be a helpful tool for observers of the Great Game – but it also has its limitations. A case in point is the renewed US-Russia confrontation. Think tanks and policy insiders easily sell the narrative that from the dark days of the Cold War to ...
More News »