Hybrid embryos could be created within months
2007 09 06
An embryo created in a laboratory
Hybrid embryos containing both human and animal material could be created in British laboratories within months.
The controversial research was given a green light yesterday by the UK's fertility regulator.
A shortage of human eggs led scientists to seek permission to make hybrid embryos from human skin cells and animal eggs such as those from cows, which are plentiful in slaughterhouses.
Two teams of scientists are poised to start making cow-human hybrids for research into incurable diseases, with at least one project expected to start by the end of the year.
Stem cell expert Dr Stephen Minger, who wants to use the embryos to study conditions such as Alzheimer's, Parkinson's and motor neurone disease, said the work could "revolutionise drug discovery".
But the decision by the Human Fertilisation and Embryology Authority is likely to be subject to a High Court challenge, with opponents claiming the watchdog is not entitled to rule on the issue.
Josephine Quintavalle, of the campaign group Comment on Reproductive Ethics, said last night: "There is a sense from some people that scientists should never be stopped in their tracks.
"Reproduction with animals has been taboo since the beginning of recorded time and that taboo has remained with us for a reason.
"This is tampering at a very basic level."
Britain is one of the first Western countries to approve such research.
The creation of hybrid embryos is banned in Australia and many European countries but experiments have been carried out in the Far East and the research is allowed in Canada.
The process involves removing the genetic material from the animal egg and replacing it with human DNA.
After being kick-started by an electric current, the egg would develop into an embryo from which stem cells - the body's master cells - can be harvested.
Such cells would be made available to scientists around the world to study the causes of disease and develop potential treatments.
The embryos, known as cytoplasmic, would be more than 99 per cent human.
They would have to be destroyed after 14 days and could not be implanted into women.
Scientists' hopes of using such hybrids were initially jeopardised by plans to outlaw such research under a shake-up of the ageing fertility laws.
But in May, Ministers dramatically changed their minds, with a draft bill approving the creation of hybrids for research into serious diseases as long as it is carried out by scientists licensed by the HFEA.
Yesterday, the HFEA, which is being asked to rule on two applications by scientists before the new law comes into force, approved the creation of hybrids in principle.
The final go-ahead on applications from researchers at King's College, London, and the North East Stem Cell Institute in Newcastle will rest with the authority's licence committee, due to meet in November.
Should it approve the applications, the research in Newcastle is likely to start almost immediately, while the London scientists hope to conduct their first experiments next summer.
The highly complex and labour-intensive nature of the process means that thousands of cow eggs could be used over many months to create just one hybrid embryo.
Critics say there is little evidence such intricate work will yield results and vehemently oppose the destruction of embryos that will be an inevitable part of the experiments.
Comment on Reproductive Ethics is considering a legal challenge based on the belief that the wording of current fertility laws does not give the HFEA the right to rule on the issue.
Anthony Ozimic, of the Society for Unborn Children, said there were 'grave ethical and moral objections' to the research.
"All the evidence suggests these embryos are essentially human," he said. "Yet, they will be cannibalised and killed for their stem cells.
"Patients with degenerative diseases are being exploited.
"They and their families are being sold lies and false hope by the profit-hungry biotech industry."
But Dr Minger, of King's College London, says the work is an essential part of the quest to find new drugs and therapies for devastating illnesses.
He said: "Our techniques could be also be used for various forms of cancer, for cystic fibrosis, for muscular dystrophy.
"If I was someone with Alzheimer's disease, I would say: 'What are they worrying about?'.
"The research is going to be tightly regulated by the HFEA. No cows are going to be killed, the cell lines are only going to be used for research and the embryos aren't going to be implanted."
Dr Belinda Cupid, of the Motor Neurone Disease Association, said: "There is currently no cure for motor neurone disease but allowing the use of hybrid embryos in research may revolutionise future treatment of the disease and other degenerative neurological conditions.
"The case for the use of human-animal hybrid embryos in stem cell research is compelling as it holds the potential to save lives."
The HFEA says a consultation showed the public were "at ease" with the idea when told it could pave the way for therapies for conditions such as Alzheimer's.
Although the embryos are sometimes called chimeras, after the monstrous creatures in Greek mythology, they are technically hybrids.
Chimeras contain two types of cell - one from each "parent" - while the hybrids have only one, in which the genetic material is mixed.
Article from: http://www.thisislondon.co.uk/news/
Science's new blend mixes man and beast
Chimera embryos have right to life, say bishops
Now scientists create a sheep that's 15% human
Human Cells + Animal Cells = ?
Why Embryonic Stem Cell Research? It's About Human Engineering, Not Ending Disease
Red Ice Creations Radio - Tom Horn - Nephilim Stargates: The Year 2012 and the Return of the Watchers
'Darth Venter' (J. Craig Venter) & The Archon Genomics X Prize
Patent sought on 'synthetic life'
I’ve found God, says man who cracked the genome
First genome transplant turns one species into another
Artificial life likely in 3 to 10 years
Scientist Calls For World DNA Database
Latest News from our Front Page
Boston Bomber Carjacking Unravels
2014 03 11
An exclusive WhoWhatWhy investigation has found serious factual inconsistencies in accounts provided by the only witness to the alleged confession of the Boston Marathon bombing suspects.
Why does this matter? Because this witness is the sole source for the entire publicly accepted narrative of who was behind the bombing and its aftermath—and why these events occurred.
In case we’ve forgotten how convoluted ...
3 Years On: Events, Questions Mark Fukushima Anniversary
2014 03 11
Three years on and the extent of the environmental, human and economic repercussions of the Fukushima incident continue to reveal themselves. Fukushima “fallout” is both literal in terms of radioactive materials, and figurative on a global scale. The politics and opinions around the nuclear issue are far from settled.
In Japan anti-nuclear sentiment runs high, with protesters recently marking the anniversary ...
Real Ukraine Issue: Rogue Reactors and Putin’s ’No-Bama’ Zone in Crimea
2014 03 11
Another week into the ‘Crimea Crisis’ and the kamakizi war rhetoric is still spewing out of Washington, London and their multinational corporate media arms.
You’d think it was Red Dawn all over again, only it’s not.
It all sound very impressive and pumped up in the news rooms, but is there any real substance in it – other than keeping oil and ...
Spraying Chemtrails to ’Reduce Pollution’
2014 03 11
The noxious smog choking Chinese cities is globally notorious, with photos showing the grey darkness that swallows citizens as they try to go about their lives. The thick clouds sometimes turn day to night, and wreak havoc for those with respiratory ailments. Reports of how toxic and damaging the smog is to humans and the environment completes the nightmare scenario, ...
Missing flight: Why are the phantom phones ringing FOUR DAYS after mystery disappearance? (Perhaps not underwater?)
2014 03 11
Many desperate and devastated families of the missing Malaysian Airlines Flight are clinging to hope. For days they have been waiting anxiously for any word from officials about the status or location of the plane and its 239 passengers. Some of the family members have been able to ’connect’ to their missing loved ones via cellphones - the phones ring ...
|More News » |