Japanese hospital to test new cancer therapy
2011 01 20

From: Google/AFP

Medical researchers in Japan say they will start the world’s first clinical studies of a radiation therapy using accelerator-based neutron beams to kill cancer cells.

The National Cancer Centre in Tokyo and a Japanese medical equipment maker -- Cancer Intelligence Care Systems -- plan to start the studies using "boron neutron capture therapy (BNCT)" in three years, the centre said.

The BNCT is an innovative radiation treatment which kills cancer cells selectively without side-effects, but it requires a massive facility including a nuclear reactor to produce neutron beams.

By using a particle accelerator, which is cheaper, safer and smaller than a reactor, it will become feasible for a hospital to provide the therapy on actual patients, the centre told journalists Tuesday.

The centre hopes to try the special radiation therapy on patients with cancers that have been difficult to treat in conventional procedures, such as brain tumors and melanoma, it said.


Article from: google.com


The boron neutron capture therapy(BNCT) is a promising method of cancer treatment in principle, which kills cancer cells selectively by the use of cancer seeking boron compound and the neutron irradiation. Source





Boron neutron capture therapy for brain tumours
From: CancerHelp.org.uk

Boron neutron capture therapy (BNCT) is an experimental way of giving radiotherapy that has been used in trials with glioblastoma multiforme (grade 4 glioma). There are concerns that the treatment causes severe side effects, so trials continue in Europe and the USA. The trials are looking into using this treatment after surgery to try to reduce the risk of the brain tumours coming back.

BNCT is really a combination of treatment with boron and fast neutrons. Radiotherapy using neutrons can get rid of glioblastoma cells. Unfortunately, at the dose needed to do this, too much damage is caused to healthy brain tissue.

In BNCT, boron is injected into the bloodstream and collects in tumour cells. The next stage of the treatment is external radiotherapy with low energy neutrons. The boron molecules give off radiation within the brain tumour cells when the external neutron radiation hits them. This enhances the radiation dose by about 2 or 3 times. So, a lower dose of neutron radiotherapy can be given. This makes it less likely that the neutrons will cause damage.

Unfortunately, there have been reports of damage being caused by the boron in the brain. This was an unexpected complication and more research needs to be done to confirm or deny this. There are no trials for patients going on in the UK at the moment. BNCT research is going on here, but it is still at the pre-clinical (laboratory) stage. Hopefully, this will lead to an early phase clinical trial soon.

There is an early phase trial in the US for people with newly diagnosed glioblastoma multiforme. The trial is testing BNCT with a chemotherapy drug called temozolamide. Early phase trials look at side effects, doses and whether there seems to be a response for a particular cancer. It is only in later phase 3 trials that we can see if a new treatment works any better than an existing treatment. So it will be some years before we have any long term results for BNCT.


Article from: cancerhelp.org.uk





Related Articles
Radioactive Cancer Patients: Public Health Menace?
Cancer ’is purely man-made’ say scientists after finding almost no trace of disease in Egyptian mummies
Breakthrough for cancer-hit Tasmanian Devils
Socioeconomic status predicts survival of cancer patients
US War Crimes: Cancer Rate in Fallujah Worse than Hiroshima
Major Cancer Charity to Admit It Was Wrong About Suntanning
Sunscreen scam? We spend millions on protection, so why is skin cancer still on the rise?
Insurance company targets breast cancer victims; cancels policies without their knowledge
He’s in the Army now: Wife’s cancer prompts man to enlist
Sick of pink: Commodifying Cancer


Latest News from our Front Page

Exponential growth of Ashkenazi Jews following a Medieval population bottleneck
2014 09 17
A recent paper by Marta Costa et al. found that around 80% of Ashkenazi mitochondrial DNA had a prehistoric European origin (and ruled out the Khazar hypothesis). Combined with previous Y chromosome studies indicating that the male line is Middle Eastern, the results suggested a scenario in which Jewish males married European females after traveling to Europe. Now another paper, ...
Bankers Rule: City of London vs. Scottish Independence
2014 09 17
Now that the independence referendum is too close to call, the bankers express their worry. The media blitz ramps up to tip the outcome. Scottish independence has finally rattled the City of London has the usual banksters forecasting the dislocations from a currency panic. Scotland has a long and noteworthy history of banking. Money, savings and investing is entrenched in the ...
French separatists want Scots to say "yes"
2014 09 17
Separatist leaders in Brittany, Corsica and the French Basque Country will watch with interest as Scotland votes on independence next week, but they don’t expect France to follow the UK’s lead any time soon. Pro-independence activists point to the fact they have their own languages and cultural identities. France, however, remains a deeply centralized country and any talk of a negotiated ...
Devil’s Deal: US-Backed Syrian Rebels Already Signed Pact with ISIS Prior to Haines Beheading
2014 09 17
While Washington considers appropriating half a billion in funds to the Syrian rebels, we now learn that opposition groups the Free Syrian Army (FSA) and al Qaeda affiliate ‘al Nusra Front’, have officially aligned themselves with ISIS… Despite grand words by US President Obama and British PM David Cameron, here’s what’s really behind their plan to bomb ISIS in Syria… In a ...
World War III for Dummies
2014 09 16
A Step-by-Step Guide to Understanding the Present World Situation. 1998 - 2000 Powerful elites and influential think tanks forecast a coming period of American aggression. Zbigniew Brzezinski speaks for the Globalist faction of the western PRC (Predatory Ruling Class) in ’The Grand Chessboard’, a book in which he openly advocates for bolder American action in dominating the Eurasian land mass. During this ...
More News »