Japanese hospital to test new cancer therapy
2011 01 20

From: Google/AFP

Medical researchers in Japan say they will start the world’s first clinical studies of a radiation therapy using accelerator-based neutron beams to kill cancer cells.

The National Cancer Centre in Tokyo and a Japanese medical equipment maker -- Cancer Intelligence Care Systems -- plan to start the studies using "boron neutron capture therapy (BNCT)" in three years, the centre said.

The BNCT is an innovative radiation treatment which kills cancer cells selectively without side-effects, but it requires a massive facility including a nuclear reactor to produce neutron beams.

By using a particle accelerator, which is cheaper, safer and smaller than a reactor, it will become feasible for a hospital to provide the therapy on actual patients, the centre told journalists Tuesday.

The centre hopes to try the special radiation therapy on patients with cancers that have been difficult to treat in conventional procedures, such as brain tumors and melanoma, it said.


Article from: google.com


The boron neutron capture therapy(BNCT) is a promising method of cancer treatment in principle, which kills cancer cells selectively by the use of cancer seeking boron compound and the neutron irradiation. Source





Boron neutron capture therapy for brain tumours
From: CancerHelp.org.uk

Boron neutron capture therapy (BNCT) is an experimental way of giving radiotherapy that has been used in trials with glioblastoma multiforme (grade 4 glioma). There are concerns that the treatment causes severe side effects, so trials continue in Europe and the USA. The trials are looking into using this treatment after surgery to try to reduce the risk of the brain tumours coming back.

BNCT is really a combination of treatment with boron and fast neutrons. Radiotherapy using neutrons can get rid of glioblastoma cells. Unfortunately, at the dose needed to do this, too much damage is caused to healthy brain tissue.

In BNCT, boron is injected into the bloodstream and collects in tumour cells. The next stage of the treatment is external radiotherapy with low energy neutrons. The boron molecules give off radiation within the brain tumour cells when the external neutron radiation hits them. This enhances the radiation dose by about 2 or 3 times. So, a lower dose of neutron radiotherapy can be given. This makes it less likely that the neutrons will cause damage.

Unfortunately, there have been reports of damage being caused by the boron in the brain. This was an unexpected complication and more research needs to be done to confirm or deny this. There are no trials for patients going on in the UK at the moment. BNCT research is going on here, but it is still at the pre-clinical (laboratory) stage. Hopefully, this will lead to an early phase clinical trial soon.

There is an early phase trial in the US for people with newly diagnosed glioblastoma multiforme. The trial is testing BNCT with a chemotherapy drug called temozolamide. Early phase trials look at side effects, doses and whether there seems to be a response for a particular cancer. It is only in later phase 3 trials that we can see if a new treatment works any better than an existing treatment. So it will be some years before we have any long term results for BNCT.


Article from: cancerhelp.org.uk





Related Articles
Radioactive Cancer Patients: Public Health Menace?
Cancer ’is purely man-made’ say scientists after finding almost no trace of disease in Egyptian mummies
Breakthrough for cancer-hit Tasmanian Devils
Socioeconomic status predicts survival of cancer patients
US War Crimes: Cancer Rate in Fallujah Worse than Hiroshima
Major Cancer Charity to Admit It Was Wrong About Suntanning
Sunscreen scam? We spend millions on protection, so why is skin cancer still on the rise?
Insurance company targets breast cancer victims; cancels policies without their knowledge
He’s in the Army now: Wife’s cancer prompts man to enlist
Sick of pink: Commodifying Cancer


Latest News from our Front Page

Easter - Christian or Pagan?
2014 04 18
From: truthbeknown.com Contrary to popular belief, Easter does not represent the "historical" crucifixion and resurrection of Jesus Christ. In reality, the gospel tale reflects the annual "crossification" of the sun through the vernal equinox (Spring), at which time the sun is "resurrected," as the day begins to become longer than the night. Rather than being a "Christian" holiday, Easter celebrations date back ...
Man-Made Blood Might Be Used in Transfusions by 2016
2014 04 18
Researchers in the U.K. have created the first man-made red blood cells of high enough quality to be introduced into the human body The premise of the HBO show and book series True Blood revolves around a technological breakthrough: scientists figure out how to synthesize artificial human blood, which, as an ample new source of non-human food, allows vampires to "come ...
The Trials of the Cherokee Were Reflected In Their Skulls
2014 04 18
Researchers from North Carolina State University and the University of Tennessee have found that environmental stressors – from the Trail of Tears to the Civil War – led to significant changes in the shape of skulls in the eastern and western bands of the Cherokee people. The findings highlight the role of environmental factors in shaping our physical characteristics. ...
Our Fears May Be Shaped by Ancestral Trauma
2014 04 18
Last December, an unsettling Nature Neuroscience study found that mice who were taught to associate the smell of cherry blossoms with pain produced offspring who feared the smell of cherry blossoms, even if they had never been exposed to it before. We knew that the process was epigenetic—that it was not hard-wired in the permanent genetic structure of the mouse—but ...
Did vitamin B3 come from space?
2014 04 17
Ancient Earth might have had an extraterrestrial supply of vitamin B3 delivered by carbon-rich meteorites, according to a new analysis. The result supports a theory that the origin of life may have been assisted by a supply of key molecules created in space and brought to Earth by comet and meteor impacts. "It is always difficult to put a value on ...
More News »