Japanese hospital to test new cancer therapy
2011 01 20

From: Google/AFP

Medical researchers in Japan say they will start the world’s first clinical studies of a radiation therapy using accelerator-based neutron beams to kill cancer cells.

The National Cancer Centre in Tokyo and a Japanese medical equipment maker -- Cancer Intelligence Care Systems -- plan to start the studies using "boron neutron capture therapy (BNCT)" in three years, the centre said.

The BNCT is an innovative radiation treatment which kills cancer cells selectively without side-effects, but it requires a massive facility including a nuclear reactor to produce neutron beams.

By using a particle accelerator, which is cheaper, safer and smaller than a reactor, it will become feasible for a hospital to provide the therapy on actual patients, the centre told journalists Tuesday.

The centre hopes to try the special radiation therapy on patients with cancers that have been difficult to treat in conventional procedures, such as brain tumors and melanoma, it said.


Article from: google.com


The boron neutron capture therapy(BNCT) is a promising method of cancer treatment in principle, which kills cancer cells selectively by the use of cancer seeking boron compound and the neutron irradiation. Source





Boron neutron capture therapy for brain tumours
From: CancerHelp.org.uk

Boron neutron capture therapy (BNCT) is an experimental way of giving radiotherapy that has been used in trials with glioblastoma multiforme (grade 4 glioma). There are concerns that the treatment causes severe side effects, so trials continue in Europe and the USA. The trials are looking into using this treatment after surgery to try to reduce the risk of the brain tumours coming back.

BNCT is really a combination of treatment with boron and fast neutrons. Radiotherapy using neutrons can get rid of glioblastoma cells. Unfortunately, at the dose needed to do this, too much damage is caused to healthy brain tissue.

In BNCT, boron is injected into the bloodstream and collects in tumour cells. The next stage of the treatment is external radiotherapy with low energy neutrons. The boron molecules give off radiation within the brain tumour cells when the external neutron radiation hits them. This enhances the radiation dose by about 2 or 3 times. So, a lower dose of neutron radiotherapy can be given. This makes it less likely that the neutrons will cause damage.

Unfortunately, there have been reports of damage being caused by the boron in the brain. This was an unexpected complication and more research needs to be done to confirm or deny this. There are no trials for patients going on in the UK at the moment. BNCT research is going on here, but it is still at the pre-clinical (laboratory) stage. Hopefully, this will lead to an early phase clinical trial soon.

There is an early phase trial in the US for people with newly diagnosed glioblastoma multiforme. The trial is testing BNCT with a chemotherapy drug called temozolamide. Early phase trials look at side effects, doses and whether there seems to be a response for a particular cancer. It is only in later phase 3 trials that we can see if a new treatment works any better than an existing treatment. So it will be some years before we have any long term results for BNCT.


Article from: cancerhelp.org.uk





Related Articles
Radioactive Cancer Patients: Public Health Menace?
Cancer ’is purely man-made’ say scientists after finding almost no trace of disease in Egyptian mummies
Breakthrough for cancer-hit Tasmanian Devils
Socioeconomic status predicts survival of cancer patients
US War Crimes: Cancer Rate in Fallujah Worse than Hiroshima
Major Cancer Charity to Admit It Was Wrong About Suntanning
Sunscreen scam? We spend millions on protection, so why is skin cancer still on the rise?
Insurance company targets breast cancer victims; cancels policies without their knowledge
He’s in the Army now: Wife’s cancer prompts man to enlist
Sick of pink: Commodifying Cancer


Latest News from our Front Page

Recent Israeli Synagogue Attack, a Possible False Flag?
2014 11 21
Dear Friends - I woke up yesterday morning to see a newspaper lying on the kitchen table with the front page proclaiming that five people were slain in an Israeli synagogue after a so-called "Palestinian attack." Some members of the media said that four people were killed, others said five, so it seems like that there was some confusion (or ...
The Michael Brown Shooting, Race Baiting for Political Power and Militarization of the Police
2014 11 21
From Youtube: The evidence clearly shows that Officer Darren Wilson was justified in shooting Michael Brown, so why is this case being hyped by the mainstream media and the leftist political establishment?
Ancient Aryan Mummies and Pyramids of China
2014 11 21
After years of controversy and political intrigue, archaeologists using genetic testing have proven that Caucasians roamed China’s Tarim Basin thousands of years before East Asian people arrived. The research, which the Chinese government has appeared to have delayed making public out of concerns of fueling Uighur Muslim separatism in its western-most Xinjiang region, is based on a cache of ancient dried-out ...
Detekt: A New Malware Detection Tool That Can Expose Illegitimate State Surveillance
2014 11 21
Recent years have seen a boom in the adoption of surveillance technology by governments around the world, including spyware that provides its purchasers the unchecked ability to target remote Internet users’ computers, to read their personal emails, listen in on private audio calls, record keystrokes and passwords, and remotely activate their computer’s camera or microphone. EFF, together with Amnesty International, ...
New UK spy chief says tech giants aid terrorism, privacy not ‘absolute right’
2014 11 21
Robert Hannigan, the new head of GCHQ The new head of Britain’s GCHQ, the UK equivalent of the NSA in the U.S., said he believes privacy is not an absolute right and that tech giants must open themselves up to intelligence agencies. “GCHQ is happy to be part of a mature debate on privacy in the digital age,” Hannigan said. “But privacy ...
More News »