Body’s Own Stem Cells Can Lead to Tooth Regeneration
A new technique can orchestrate stem cells to migrate to a three-dimensional scaffold infused with growth factor, holding the translational potential to yield an anatomically correct tooth in as soon as nine weeks once implanted.
Human molar scaffolding from the laboratory of Dr Jeremy Mao.
This has been pioneered in the Tissue Engineering and Regenerative Medicine Laboratory of Dr Jeremy Mao, a professor of dental medicine at Columbia University Medical Center in New York.
An animal-model study has shown that by homing stem cells to a scaffold made of natural materials and integrating them into surrounding tissue, there is no need to use harvested stem cell lines or create an environment outside of the body where the tooth is grown and then implanted once it has matured. Instead, the tooth can be grown in the socket where it will integrate with surrounding tissue in ways that are impossible with hard metals or other materials.
‘These findings represent the first report of regeneration of anatomically shaped tooth-like structures in vivo, and by cell homing without cell delivery,’ write Dr Mao and his colleagues in the research paper. ‘The potency of cell homing is substantiated not only by cell recruitment into scaffold micro-channels, but also by the regeneration of periodontal ligaments and newly formed alveolar bone.’
Dr Mao went on to state: ‘A key consideration in tooth regeneration is finding a cost-effective approach that can translate into therapies for patients who cannot afford or who aren’t good candidates for dental implants. Cell-homing-based tooth regeneration may provide a tangible pathway toward clinical translation.’
Article from: irishdentist.ie
Columbia University Medical Center
The Fountain of Regeneration - Isis in Paris
Human Heart Regenerates Cells Automatically: One Percent Each Year
Regeneration of Cells (Video)
Super Stemmys - Stem Cell Children´s Book
New Stem Cell Research: Men & Women not needed for first step in Making babies
Liposuction leftovers are ’liquid gold’ for stem cell researchers
Obama lifts Bush restrictions on stem cell research
Selling Stem Cells
Henrietta’s ‘Immortal’ Cells
Latest News from our Front Page
41% of Americans Support Criminalizing "Hate Speech"
The following are from a recent poll about what some are calling on for "hate speech"
1. Support for Hate Crimes Legislation
Do you support or oppose the federal law that requires increased penalties for hate crimes committed on the basis of the actual or perceived race, color, religion, national origin, ethnicity, or gender of any person?
2. Support for Expanding Hate Crimes
FBI Admits No Major Cases Cracked with Patriot Act Snooping Powers
FBI agents canâ€™t point to any major terrorism cases theyâ€™ve cracked thanks to the key snooping powers in the Patriot Act, the Justice Departmentâ€™s inspector general said in a report Thursday that could complicate efforts to keep key parts of the law operating.
Inspector General Michael E. Horowitz said that between 2004 and 2009, the FBI tripled its use of bulk ...
Sweetener Stevia Was Once Hailed As An Anti-Fertility Agent for Population Reduction
Maybe it's not so sweet now... If you've thought stevia, the natural alternative to sugar and artificial sweetners with aspartame, et al., is too good to be true, there may be a catch. Check out this textbook written in 1970 by Paul and Anne Ehrlich, the precursor to the textbook Ecoscience they wrote with Obama Science Czar John P. Holdren ...
TPP Aproved: Senate Republicans Give Obama New Powers - Details Remain 'Classified'
President Obama won a big victory for his trade agenda Friday with the Senateâ€™s approval of fast-track legislation that could make it easier for him to complete a wide-ranging trade deal that would include 11 Pacific Rim nations.
A coalition of 48 Senate Republicans and 14 Democrats voted for Trade Promotion Authority late Friday, sending the legislation to a difficult fight ...
Circumcision battle: Mom seeks release from jail after federal lawsuit is dismissed
West Boynton mother on Wednesday gave up trying to get a federal judge to stop her 4 1/2-year-old son from being circumcised as his father wishes â€” a battle that also led to her arrest May 14 on a state court warrant.
An attorney for Heather Hironimus, who lost similar legal challenges in two state courts, notified U.S. District Judge Kenneth ...
|More News » |