The Manhattan Beach Project to End Aging by 2029
2009-12-12 0:00

By Surfdaddy Orca | HPlusMagazine.com


Just as the Manhattan Project was conceived in 1942 to beat the Germans to the atomic bomb during World War II, the “Manhattan Beach Project” was founded as an “all-out assault on the world’s biggest killer – aging,” according to project organizer David A. Kekich.

An end to aging may be just as explosive as the atomic blast that occurred at Alamogordo, New Mexico during the predawn hours of July 16, 1945. It’s serious enough that members of the Obama Administration consider it to be one of the major global destabilizing forces of the next 25 years. It will require the political mastery of a scientific and societal transition built around the Nano-Info-Bio-Cogno (NBIC) roadmap.

After nine years of research and collaboration, a group of entrepreneurs and scientists – many known to h+ readers –- are disclosing their plan “to start saving up to 100,000 lives lost to aging every day, by 2029.” A Longevity Summit in November 2009 -- organized by Kekich -- brought together a number of researchers on human aging and longevity for a discussion on the state-of-the-art research, the implications of their discoveries, and round table, cross-disciplinary discussions that may lead to new and accelerated results. Here’s a video of Kekich explaining the project:


Video from: YouTube.com

The goal of the summit was “to devise scientific and business strategies with the goal of demonstrating the capability to reverse aging in an older human by 2029.” Many at the conference believe that humans are approaching something Aubrey De Grey calls “longevity escape velocity” (see the h+ article “Aubrey de Grey on ‘The Singularity’ and ‘The Methuselarity’” in Resources). This is the point at which the yearly advances in procedures for extending human life expectancy result in adding one year to the human lifespan –- potentially making death-by-aging a choice rather than a date with destiny.

Entrepreneur and futurist Ray Kurzweil opened the conference with a virtual presentation on exponential technology trends that are bringing the prospect of achieving longevity escape velocity ever closer. “We are very close to the tipping point in human longevity,” explained Kurzweil. “We are about 15 years away from adding more than one year of longevity per year to remaining life expectancy.”

University of California, Riverside biochemist Stephen Spindler reported on his research seeking caloric restriction mimetics. Research shows that restricting mice and rats to about two-thirds of their regular diet extends their healthy lifespans. For example, calorie-restricted mice live up to 50 percent longer and experience less heart disease and cancer than those who eat as much as they want. Spindler is testing a variety of compounds including pharmaceuticals to see if they mimic the effects of caloric restriction in mice.

Michael Rose, a biologist at the University of California, Irvine, talked about his work breeding long-lived fruit flies. Rose is testing the hypothesis that natural selection contributes to aging. Using artificial selection for longevity, Rose has produced fruit flies that live four times longer than normal, the human equivalent of being healthy at age 300. These “Methuselah flies” are more fecund and better at handling environmental stresses than non-selected flies.

William Andrews, head of Sierra Sciences, talked about his company’s project to identify compounds that lengthen telomeres –- repeated sequences of DNA that cap the ends of chromosomes to keep them from unraveling and to keep them from binding to other chromosomes. According to Andrews, when an adult’s telomeres get down to about 5,000 repeats they die of old age. By looking at telomere length in a blood sample, he claims to be able to predict how much time until you die a natural death. “I can tell how old you are and how long you have before you die of old age,” claims Andrews.

Stephen Coles heads the Supercentenarian Research Foundation (SRF) and wants to answer the question why some people live to be over 100 years old. Supercentenarians are people who are over 110 years old. In the world there are 76 currently validated supercentenarians, 72 are female and 4 are male. His research shows that most died of senile cardiac amyloidosis, the accumulation of amyloid fibers in their heart muscles.

John Furber, founder of Legendary Pharmaceuticals, discussed the problem of accumulating cross-linked proteins and sugars inside and outside of cells – these are the fibers that killed Coles' supercentenarians. The digestive organelles inside cells called lysosomes slowly become clogged with advanced glycation end-products (AGEs).

Nanotechnology pioneer Robert Freitas – recipient of the prestigious 2009 Feynman Prize for Theory, in recognition of his pioneering work in molecular mechanosynthesis –- gave a talk with Ralph Merkle on how medical non-biological nanotechnology will likely work in the next 20 years. “The difference between good and bad health is how your atoms are arranged,” said Merkle. The goal of medical nanotechnology is to mobilize nanobots to patrol the body and its cells repairing damage as it occurs.

The business strategy session included new media entrepreneur and Disney executive Oliver Luckett, 2008 Libertarian Party VP candidate Wayne Allyn Root, computer and biotech entrepreneur Richard Offerdahl, marketing expert John Lustyan, social media marketer Michael Terpin, Lifestar Institute COO Kevin Perrott, CEO of TA Sciences Noel Patton, filmmaker Michael Potter, marketer Joe Sugarman, computer entrepreneur Ken Weiss, and Bill Faloon, co-founder of the Life Extension Foundation.

Can you stay healthy enough to make it to 2029? If you can, you may be able to live indefinitely if you choose – although the political and societal challenges you’ll face will likely be more daunting than the ones that followed the dawning of the Atomic Era at Alamogordo in 1945.

Article from: HPlusMagazine.com




Longevity & The Holy Grail Promo

Aubrey de Grey, Artificial Intelligence, Singularity, Longevity and the Holy Grail

Red Ice Creations Radio - Michael Tsarion - The Post Human World

Sonia Barrett - Immortality and the Quest for Eternal Life

Doctors Baffled, Intrigued by Girl Who Doesn't Age



Related Articles
Aubrey de Grey, Artificial Intelligence, Singularity, Longevity and the Holy Grail
Aubrey de Grey's "Methuselarity"
When Death is an Outlaw
You Are What You Don't Eat
www.manhattanbeachproject.com
The Methuselah Manifesto
Manhattan Beach Project Longevity Summit Review
Biological Mimetics, Inc.


Latest News from our Front Page

Turkey's Erdogan threatened to flood Europe with migrants: Greek website
2016-02-09 23:04
Turkish President Tayyip Erdogan threatened in November to flood Europe with migrants if European Union leaders did not offer him a better deal to help manage the Middle East refugee crisis, a Greek news website said on Monday. Publishing what it said were minutes of a tense meeting last November, the euro2day.gr financial news website revealed deep mutual irritation and distrust ...
Will Denmark Be The First Islamic Nation In Europe?
2016-02-09 23:44
Daily headlines prove that Europe is bursting at the seams with Islamists attempting to establish Sharia law and homegrown terror plots. France is ablaze with radicals, ISIS threatens they will send Spain back to the times of the Ottoman Empire, and Britain is much too concerned with appeasing Muslims that they are doing away with their own citizens’ free speech. The ...
'Hamilton' musical: All American founders non-White, but evil King George. I hate musicals!
2016-02-09 22:43
‘Hamilton’, Lin-Manuel Miranda’s musical about the life of Alexander Hamilton, one of America’s founding fathers, is being performed on Broadway. You know it’s going to have political undertones, when you read that the first act is titled: “Immigrants : We get the job done!” In addition to Alexander Hamilton, Miranda’s musical also casts Aaron Burr, George Washington, James Madison, John Laurens, Marquis Gilbert ...
Ted Nugent Posts "Anti-Semitic" Facebook Message About Gun Control
2016-02-09 22:53
Rock musician Ted Nugent posted a message about “who is really behind gun control” on Facebook that the Anti-Defamation League slammed as "anti-Semitic". More: ADL claims 26% of all world population is “anti-semitic” The ADL and domestic spying: Roy Bullock case revisited "Antisemitism on rise across Europe in worst times since the Nazis" says "expert" to the Guardian In the post, Nugent shares a ...
Illegal immigrant is arrested over murder of American nanny in Austria after she took him in to stop him being deported - and is revealed to have raped underage girl
2016-02-09 22:20
An illegal immigrant has been arrested over the murder of an American nanny who had given him shelter at her Vienna apartment. The 24-year-old Gambian had been wanted by police since the death of Lauren Mann, 25, from Grand Junction, Colorado last month. He was arrested on Thursday in Bern, Switzerland, at an asylum center there after his mobile phone use was ...
More News »