The Manhattan Beach Project to End Aging by 2029
By Surfdaddy Orca | HPlusMagazine.com
Just as the Manhattan Project was conceived in 1942 to beat the Germans to the atomic bomb during World War II, the “Manhattan Beach Project” was founded as an “all-out assault on the world’s biggest killer – aging,” according to project organizer David A. Kekich.
An end to aging may be just as explosive as the atomic blast that occurred at Alamogordo, New Mexico during the predawn hours of July 16, 1945. It’s serious enough that members of the Obama Administration consider it to be one of the major global destabilizing forces of the next 25 years. It will require the political mastery of a scientific and societal transition built around the Nano-Info-Bio-Cogno (NBIC) roadmap.
After nine years of research and collaboration, a group of entrepreneurs and scientists – many known to h+ readers –- are disclosing their plan “to start saving up to 100,000 lives lost to aging every day, by 2029.” A Longevity Summit in November 2009 -- organized by Kekich -- brought together a number of researchers on human aging and longevity for a discussion on the state-of-the-art research, the implications of their discoveries, and round table, cross-disciplinary discussions that may lead to new and accelerated results. Here’s a video of Kekich explaining the project:
Video from: YouTube.com
The goal of the summit was “to devise scientific and business strategies with the goal of demonstrating the capability to reverse aging in an older human by 2029.” Many at the conference believe that humans are approaching something Aubrey De Grey calls “longevity escape velocity” (see the h+ article “Aubrey de Grey on ‘The Singularity’ and ‘The Methuselarity’” in Resources). This is the point at which the yearly advances in procedures for extending human life expectancy result in adding one year to the human lifespan –- potentially making death-by-aging a choice rather than a date with destiny.
Entrepreneur and futurist Ray Kurzweil opened the conference with a virtual presentation on exponential technology trends that are bringing the prospect of achieving longevity escape velocity ever closer. “We are very close to the tipping point in human longevity,” explained Kurzweil. “We are about 15 years away from adding more than one year of longevity per year to remaining life expectancy.”
University of California, Riverside biochemist Stephen Spindler reported on his research seeking caloric restriction mimetics. Research shows that restricting mice and rats to about two-thirds of their regular diet extends their healthy lifespans. For example, calorie-restricted mice live up to 50 percent longer and experience less heart disease and cancer than those who eat as much as they want. Spindler is testing a variety of compounds including pharmaceuticals to see if they mimic the effects of caloric restriction in mice.
Michael Rose, a biologist at the University of California, Irvine, talked about his work breeding long-lived fruit flies. Rose is testing the hypothesis that natural selection contributes to aging. Using artificial selection for longevity, Rose has produced fruit flies that live four times longer than normal, the human equivalent of being healthy at age 300. These “Methuselah flies” are more fecund and better at handling environmental stresses than non-selected flies.
William Andrews, head of Sierra Sciences, talked about his company’s project to identify compounds that lengthen telomeres –- repeated sequences of DNA that cap the ends of chromosomes to keep them from unraveling and to keep them from binding to other chromosomes. According to Andrews, when an adult’s telomeres get down to about 5,000 repeats they die of old age. By looking at telomere length in a blood sample, he claims to be able to predict how much time until you die a natural death. “I can tell how old you are and how long you have before you die of old age,” claims Andrews.
Stephen Coles heads the Supercentenarian Research Foundation (SRF) and wants to answer the question why some people live to be over 100 years old. Supercentenarians are people who are over 110 years old. In the world there are 76 currently validated supercentenarians, 72 are female and 4 are male. His research shows that most died of senile cardiac amyloidosis, the accumulation of amyloid fibers in their heart muscles.
John Furber, founder of Legendary Pharmaceuticals, discussed the problem of accumulating cross-linked proteins and sugars inside and outside of cells – these are the fibers that killed Coles' supercentenarians. The digestive organelles inside cells called lysosomes slowly become clogged with advanced glycation end-products (AGEs).
Nanotechnology pioneer Robert Freitas – recipient of the prestigious 2009 Feynman Prize for Theory, in recognition of his pioneering work in molecular mechanosynthesis –- gave a talk with Ralph Merkle on how medical non-biological nanotechnology will likely work in the next 20 years. “The difference between good and bad health is how your atoms are arranged,” said Merkle. The goal of medical nanotechnology is to mobilize nanobots to patrol the body and its cells repairing damage as it occurs.
The business strategy session included new media entrepreneur and Disney executive Oliver Luckett, 2008 Libertarian Party VP candidate Wayne Allyn Root, computer and biotech entrepreneur Richard Offerdahl, marketing expert John Lustyan, social media marketer Michael Terpin, Lifestar Institute COO Kevin Perrott, CEO of TA Sciences Noel Patton, filmmaker Michael Potter, marketer Joe Sugarman, computer entrepreneur Ken Weiss, and Bill Faloon, co-founder of the Life Extension Foundation.
Can you stay healthy enough to make it to 2029? If you can, you may be able to live indefinitely if you choose – although the political and societal challenges you’ll face will likely be more daunting than the ones that followed the dawning of the Atomic Era at Alamogordo in 1945.
Article from: HPlusMagazine.com
Longevity & The Holy Grail Promo
Aubrey de Grey, Artificial Intelligence, Singularity, Longevity and the Holy Grail
Red Ice Creations Radio - Michael Tsarion - The Post Human World
Sonia Barrett - Immortality and the Quest for Eternal Life
Doctors Baffled, Intrigued by Girl Who Doesn't Age
Aubrey de Grey, Artificial Intelligence, Singularity, Longevity and the Holy Grail
Aubrey de Grey's "Methuselarity"
When Death is an Outlaw
You Are What You Don't Eat
The Methuselah Manifesto
Manhattan Beach Project Longevity Summit Review
Biological Mimetics, Inc.
Latest News from our Front Page
The Josh Duggar Incident Reveals The Tactics And Hypocrisy of SJWs
Last week, In Touch Weekly broke the news that Josh Duggar, eldest son of Jim Bob and Michelle Duggar from TLCâ€™s 19 Kids and Counting, had molested five under-aged girls in 2002 and 2003. Josh, who was 14 at the time, was accused of fondling his victims, touching their breasts and genitals while they slept.
A police report was released shortly ...
15 More Men of South Asian Descent Charged With Child Sex Offences
Police in Keighley, West Yorkshire have charged 14 men and a 16-year-old boy with sex offences including the rape of a girl under the age of 16. The offences relate primarily to one female victim, with one allegation involving a second who was also under 16 at the time.
The offences are alleged to have occurred between 2011 and 2012. In ...
Anti-Semitic fliers left on Chevy Chase driveways
Five streets in Chevy Chase, Md., were papered with anti-Semitic fliers on Wednesday morning.
Montgomery County police are looking for the person or people who left the hate-filled leaflets on almost every driveway on the streets.
â€śThis is very disturbing. My community is definitely disturbed,â€ť said Jean Sperling, the village manager of Martinâ€™s Additions, the community where the fliers were found. Sperling ...
German court says ex-SS officer unfit for trial
Prosecutors in the northern German city of Hamburg have dropped their probe into a 93-year-old former Nazi SS officer. Gerhard Sommer, who suffers from dementia, allegedly took part in a World War II massacre in Italy.
Gerhard Sommer, a former company commander of a mechanized infantry division, had been accused of participating in the mass murder of 560 civilians by Nazi ...
The Age of Disinformation
I have been a professional meteorologist for 36 years. Since my debut on television in 1979, I have been an eyewitness to the many changes in technology, society, and how we communicate. I am one who embraces change, and celebrates the higher quality of life we enjoy now thanks to this progress.
But, at the same time, I realize the instant ...
|More News » |