Red Ice News

The Future is the Past

Blood of world’s oldest woman hints at limits of life
New to Red Ice? Start Here!

Blood of world’s oldest woman hints at limits of life

Source: newscientist.com


Death is the one certainty in life – a pioneering analysis of blood from one of the world’s oldest and healthiest women has given clues to why it happens.

Born in 1890, Hendrikje van Andel-Schipper was at one point the oldest woman in the world. She was also remarkable for her health, with crystal-clear cognition until she was close to death, and a blood circulatory system free of disease. When she died in 2005, she bequeathed her body to science, with the full support of her living relatives that any outcomes of scientific analysis – as well as her name – be made public.

Researchers have now examined her blood and other tissues to see how they were affected by age.

What they found suggests, as we could perhaps expect, that our lifespan might ultimately be limited by the capacity for stem cells to keep replenishing tissues day in day out. Once the stem cells reach a state of exhaustion that imposes a limit on their own lifespan, they themselves gradually die out and steadily diminish the body’s capacity to keep regenerating vital tissues and cells, such as blood.

Two little cells

In van Andel-Schipper’s case, it seemed that in the twilight of her life, about two-thirds of the white blood cells remaining in her body at death originated from just two stem cells, implying that most or all of the blood stem cells she started life with had already burned out and died.

"Is there a limit to the number of stem cell divisions, and does that imply that there’s a limit to human life?" asks Henne Holstege of the VU University Medical Center in Amsterdam, the Netherlands, who headed the research team. "Or can you get round that by replenishment with cells saved from earlier in your life?" she says.

The other evidence for the stem cell fatigue came from observations that van Andel-Schipper’s white blood cells had drastically worn-down telomeres – the protective tips on chromosomes that burn down like wicks each time a cell divides. On average, the telomeres on the white blood cells were 17 times shorter than those on brain cells, which hardly replicate at all throughout life.

The team could establish the number of white blood cell-generating stem cells by studying the pattern of mutations found within the blood cells. The pattern was so similar in all cells that the researchers could conclude that they all came from one of two closely related "mother" stem cells.

Point of exhaustion

"It’s estimated that we’re born with around 20,000 blood stem cells, and at any one time, around 1000 are simultaneously active to replenish blood," says Holstege. During life, the number of active stem cells shrinks, she says, and their telomeres shorten to the point at which they die – a point called stem-cell exhaustion.

Holstege says the other remarkable finding was that the mutations within the blood cells were harmless – all resulted from mistaken replication of DNA during van Andel-Schipper’s life as the "mother" blood stem cells multiplied to provide clones from which blood was repeatedly replenished.

She says this is the first time patterns of lifetime "somatic" mutations have been studied in such an old and such a healthy person. The absence of mutations posing dangers of disease and cancer suggest that van Andel-Schipper had a superior system for repairing or aborting cells with dangerous mutations.

[...]

Read the full article at: newscientist.com



READ: Henrietta’s ‘Immortal’ Cells



Tune into Red Ice Radio and Radio 3Fourteen:

Stanley Bass - Natural Hygiene, Nature Cure & Theosophy

Lorraine Day - Food, Health, Disease & The New World Order

Dr. Andrew Saul - The War on Vitamins & Nutrition

Ken Rohla - Hour 1 - Natural Health, Free Energy, MLK Assassination

Gregg Braden - Crisis in Thinking & False Assumptions of an Incomplete Science

Howard Martin - Heartmath Institute, Heart Based Living & The Global Coherence Initiative

Sonia Barrett - Immortality and the Quest for Eternal Life

Sonia Barrett & Sharry Edwards - The Business of Disease

Rick Simpson - Hour 1 - Hemp Oil Cancer Cure

Bruce Lipton - The Biology of Belief

Rudy Mazzocchi - Black Market of Human Organ Transplants

Michael Tsarion - The Post Human World

Comments

We're Hiring

We are looking for a professional video editor, animator and graphics expert that can join us full time to work on our video productions.

Apply

Help Out

Sign up for a membership to support Red Ice. If you want to help advance our efforts further, please:

Donate

Tips

Send us a news tip or a
Guest suggestion

Send Tip

Related News

Young Woman Fighting for Life After Syrian ‘Child’ Migrant Gang Knife Attack
Young Woman Fighting for Life After Syrian ‘Child’ Migrant Gang Knife Attack
Divorcee Lauren Southern Backtracks on Trad Wife Life & Takes Hits At The Right
Divorcee Lauren Southern Backtracks on Trad Wife Life & Takes Hits At The Right

Archives Pick

Red Ice T-Shirts

Red Ice Radio

3Fourteen

Con Inc., J6 Political Prisoners & The Pedophile Problem
Kim Coulter - Con Inc., J6 Political Prisoners & The Pedophile Problem
Why European Culture, Art and Beauty Matter
Gifts - Why European Culture, Art and Beauty Matter

TV

Laughter: The New Weapon Of The Far-Right
Laughter: The New Weapon Of The Far-Right
London’s Fourth Plinth To Get Fat Black “Everywoman” Statue
London’s Fourth Plinth To Get Fat Black “Everywoman” Statue

RSSYoutubeGoogle+iTunesSoundCloudStitcherTuneIn

Design by Henrik Palmgren © Red Ice Privacy Policy