Mouse cloned from drop of blood
2013-06-27 0:00

By Helen Briggs | BBC

Scientists in Japan have cloned a mouse from a single drop of blood.

Circulating blood cells collected from the tail of a donor mouse were used to produce the clone, a team at the Riken BioResource Center reports in the journal Biology of Reproduction.

The female mouse lived a normal lifespan and could give birth to young, say the researchers.

Scientists at a linked institute recently created nearly 600 exact genetic copies of one mouse.

Mice have been cloned from several different sources of donor cells, including white blood cells found in the lymph nodes, bone marrow and liver.

The Japanese research group investigated whether circulating blood cells could also be used for cloning.

Their aim was to find an easily available source of donor cells to clone scientifically valuable strains of laboratory mice.


The mouse was cloned from a blood cell

The team, led by Atsuo Ogura, of Riken BioResource Center in Tsukuba, took blood from the tail of a donor mouse, isolated the white blood cells, and used the nuclei for cloning experiments, using the same technique that produced Dolly the sheep in Edinburgh.

The process, known as somatic cell nuclear transfer, involves transferring the nucleus from an adult body cell - such as a blood or skin cell - into an unfertilised egg that has had its nucleus removed.

Reporting their findings in the US journal, Biology of Reproduction, the scientists said the study "demonstrated for the first time that mice could be cloned using the nuclei of peripheral blood cells".

Invaluable strains

They added: "These cells could be used for cloning immediately after collection and no donor animals need to be euthanised.

"This technique would be applicable for generating genetic copies of invaluable strains of mice, which cannot be preserved by other assisted reproductive techniques such as conventional in vitro fertilisation or intracytoplasmic sperm injection."

Scientists in Japan have years of experience in cloning mice.

A team at a linked institute recently revealed they had produced almost 600 mice from one donor mouse after 25 consecutive rounds of cloning.

[...]

Read the full article at: bbc.co.uk





Related Articles


Latest News from our Front Page

Minister of Migration attacked by asylum seeker with fire extinguisher
2015-03-27 2:12
Sweden’s Minister of Justice & Migration also known as Morgan “only 1%” Johansson, has been attacked with a fire extinguisher when he visited an asylum home for future Swedes. Regional newspaper, Kristiandstadsbladet reported that a man who had been living at the home for a couple of weeks grabbed a fire extinguisher and sprayed foam all over the minister who didn’t ...
Hollywood agents: Difficult for white actors to find work now that shows required ‘to go ethnic’
2015-03-27 1:51
According to an article by Nellie Andreeva published yesterday at Deadline Hollywood, the television landscape has shifted so much this season that white actors are finding it increasingly difficult to find roles. In addition to new hit shows with mostly minority casts — Black-ish, Empire, Fresh Off the Boat, and How to Get Away with Murder — shows that were originally ...
Congratulations Pussy Porters!
2015-03-26 18:52
Mural paid for by the government, decorates a Swedish school. On International Women’s day Julia Caesar published this chronicle in Swedish on Snaphanen which I’ve translated but prior to reading it I’d like to provide you with some background information on certain terms which are incomprehensible to non-Swedes. First and foremost “pussy porter” and “penis porter” are terms that third-wave feminists in ...
Germanwings co-pilot appears to have crashed plane deliberately – prosecutor
2015-03-26 18:08
The Germanwings co-pilot seemed to have crashed the plane deliberately, killing 150 people on board. The co-pilot wouldn’t let the captain inside the cabin, with the “intension to destroy” the jet, the French prosecutor said at a press conference. Follow RT’s live updates on investigation into Germanwings plane crash The Germanwings co-pilot was identified as Andreas Lubitz. The captain was between 30 ...
Sweden adds gender-neutral pronoun to dictionary
2015-03-25 19:38
The official dictionary of the Swedish language will introduce a gender-neutral pronoun in April, editors at the Swedish Academy have announced. “Hen” will be added to “han” (he) and “hon” (she) as one of 13,000 new words in the latest edition of the Swedish Academy’s SAOL. The pronoun is used to refer to a person without revealing their gender – either because ...
More News