Stanford researchers have turned a dreary gray brain into an object as transparent as apricot Jell-O -- an approach that will reveal new secrets into the most mysterious of organs.
The process, called CLARITY, transforms the brain’s tissue by replacing opaque fat with a clear gel, creating a limpid organ with all of its essential circuitry intact and in place.
"Brain tissue is very dense," said researcher Kwanghun Chung. "We have developed a technique that makes tissue transparent ... so we can visualize the architecture, necessary to understand the function of the complex organ."
The technique ushers in a new era of whole-organ imaging, offering hope for improving the study of such devastating neurological disorders such as autism, schizophrenia, Alzheimer’s disease and Parkinson’s disease.
It was conceived by a team led by bioengineer and psychiatrist Dr. Karl Deisseroth, one of the 15 experts on the "dream team" that will map out the goals for the $100 million brain research initiative announced April 2 by President Obama.
"This feat of chemical engineering promises to transform the way we study the brain’s anatomy and how disease changes it," according to a prepared statement by Dr. Thomas Insel, director of the National Institute of Mental Health.
Three-dimensional view of stained hippocampus showing fluorescent-expressing neurons (green), connecting interneurons (red) and supporting glia (blue).
Horrifying accidents at infectious disease labs hidden from the public, ‘cloaked in secrecy’ 2014 08 26 Literally hundreds of incidents involving viruses, bacteria and toxins that pose major bioterror risks to both people and agriculture have been reported to federal regulators from 2008 through 2012, according to government reports obtained and reviewed by USA Today.
More than half of the over 1,100 incidents were serious enough that laboratory workers had to have medical evaluations and/or treatment, the ...
Those Who Know They’re Dreaming Are Savvier When Awake 2014 08 26 It’s probably fair to assume that at this moment, you are, in fact, awake. You’re reading; you’re scrolling; sometime in the not-too-distant past, you somehow made your way to The Atlantic’s website. All waking activities.
But let’s say, hypothetically, that as you’re reading this, the floor and everything else beneath you dissolve, leaving your body floating where your chair had been ...
Kiev’s bloody eastern Ukraine campaign 2014 08 26
Russia delivered humanitarian aid to the besieged city of Lugansk as fighting between the Ukrainian army and self-defense forces continues in eastern Ukraine. The conflict has claimed the lives of at least 2,000 people and displaced over 300,000.
VIDEO: Ukraine: Russian aid handed out in Lugansk
Tuesday, August 26
The latest UN figures show that the number of killed and wounded ...
History Repeats: Dead Blondes on a Mountain Top 2014 08 26 The blonds of Iraq; hunted like dogs to the top of a mountain.
The shocking headline from the August 14 London Daily Mail declared:
’ISIS want to impregnate Yazidi women and smash our blond bloodline’: Fears grow for the 300 women kidnapped from Sinjar’
The Yazidi minority of Iraq is of Aryan descent (like most Europeans) and has retained much of its ...
Naturally High Fluoride Levels in Private Wells May Be Linked With IQ Decline 2014 08 26 Certain kinds of granite contain high levels of fluoride, increasing the concentration in private wells drawing it from the water. Newly available data, released in recent months, indicates dangerously high levels of fluoride in private wells. In some cases, the wells contain more than double the level that the U.S. Environmental Protection Agency has deemed the acceptable maximum exposure level ...