Stanford researchers have turned a dreary gray brain into an object as transparent as apricot Jell-O -- an approach that will reveal new secrets into the most mysterious of organs.
The process, called CLARITY, transforms the brain’s tissue by replacing opaque fat with a clear gel, creating a limpid organ with all of its essential circuitry intact and in place.
"Brain tissue is very dense," said researcher Kwanghun Chung. "We have developed a technique that makes tissue transparent ... so we can visualize the architecture, necessary to understand the function of the complex organ."
The technique ushers in a new era of whole-organ imaging, offering hope for improving the study of such devastating neurological disorders such as autism, schizophrenia, Alzheimer’s disease and Parkinson’s disease.
It was conceived by a team led by bioengineer and psychiatrist Dr. Karl Deisseroth, one of the 15 experts on the "dream team" that will map out the goals for the $100 million brain research initiative announced April 2 by President Obama.
"This feat of chemical engineering promises to transform the way we study the brain’s anatomy and how disease changes it," according to a prepared statement by Dr. Thomas Insel, director of the National Institute of Mental Health.
Three-dimensional view of stained hippocampus showing fluorescent-expressing neurons (green), connecting interneurons (red) and supporting glia (blue).
60 Years of Research Links Gluten Grains to Schizophrenia 2015-03-31 1:05
Does the consumption of gluten-containing grains contribute to psychiatric disorders such as schizophrenia?
Believe it or not, this question has been asked for well over 60 years by researchers who stumbled upon evidence that the removal of gluten from the diet results in improved symptoms, or conversely, that gluten grain consumption leads to higher prevalence of both neurological and psychiatric problems.
A Sour Deception: Citric Acid Comes From GMO Black Mold, Not Fruit 2015-03-30 23:32
Just what is your food made of, anyway? Try industrial synthesis, genetically modified mold secretions, hydrochloric acid, mercury-contaminated caustic soda, ferrocyanideâ€¦ and, of course, lots of GMO corn.
If common ingredients like â€ścitric acidâ€ť and â€śascorbic acid (Vitamin C)â€ť sound normal and familiar enough that you practically conjure up an image of the flourishing orchard they were grown in â€“ then ...
Thousands of migrants dumped on Britain as French wriggle out of border promise 2015-03-30 19:56
Thousands of migrants could be dumped on Britainâ€™s doorstep if France tears up a historic border agreement, it was claimed last night.
Officials have vowed to do â€śeverything in their powerâ€ť to wriggle out of a treaty moving the UK border to Calais.
The besieged townâ€™s mayor Natacha Bouchart is prepared to spark a major diplomatic row by opening the frontier ...
Richard III laid to rest at Leicester Cathedral 2015-03-30 18:36
King Richard III was today laid to rest at Leicester Cathedral - more than 500 years after his death in battle.
The monarch, who reigned from 1483 to 1485, was the last of the Plantagenet dynasty.
Actor Benedict Cumberbatch read a poem by Carol Ann Duffy during the service. Also in attendance was Robert Lindsay, who played Richard III in a version ...
Sweden - A new paradise for Romani beggars 2015-03-30 17:33
Thanks to the European Union and freedom of movement that follows with membership Sweden has been flooded with gypsies from Eastern Europe.
Most member states have cracked down hard on the phenomenon of organized begging with legislation and forceful evictions so the Romani (colloquially known as Gypsies) who are engaged in this venture have moved their business to the country where ...