Stanford researchers have turned a dreary gray brain into an object as transparent as apricot Jell-O -- an approach that will reveal new secrets into the most mysterious of organs.
The process, called CLARITY, transforms the brain’s tissue by replacing opaque fat with a clear gel, creating a limpid organ with all of its essential circuitry intact and in place.
"Brain tissue is very dense," said researcher Kwanghun Chung. "We have developed a technique that makes tissue transparent ... so we can visualize the architecture, necessary to understand the function of the complex organ."
The technique ushers in a new era of whole-organ imaging, offering hope for improving the study of such devastating neurological disorders such as autism, schizophrenia, Alzheimer’s disease and Parkinson’s disease.
It was conceived by a team led by bioengineer and psychiatrist Dr. Karl Deisseroth, one of the 15 experts on the "dream team" that will map out the goals for the $100 million brain research initiative announced April 2 by President Obama.
"This feat of chemical engineering promises to transform the way we study the brain’s anatomy and how disease changes it," according to a prepared statement by Dr. Thomas Insel, director of the National Institute of Mental Health.
Three-dimensional view of stained hippocampus showing fluorescent-expressing neurons (green), connecting interneurons (red) and supporting glia (blue).
Pressure from the United Patriots Front Stops Mosque Plan 2016-04-28 20:10
Pressure from the United Patriots Front appears to have killed off a mosque development in Narre Warren North.
The City of Casey council now looks likely to withhold planning approval for the development in a special meeting set for Tuesday night.
A council report, to be considered by councillors on Tuesday, recommends that the approval be blocked.
The mosque opponents’ cause has been helped by councillor ...
Police face questions over the influence of the Freemasons 2016-04-28 20:48
South Yorkshire Police today face questions over whether powerful 'secret society' the Freemasons held sway over the force at the time of Hillsborough.
Families of victims say that officers who were Masons were promoted into powerful positions despite being ill-equipped, including match commander David Duckenfield.
Duckenfield told the fresh inquests he had been a Freemason since 1975 and became head of his ...
England Bans its Own Flag to Avoid Offending Muslims 2016-04-27 2:23 St. George's Cross "racist" towards immigrants
Government officials said their city was ‘too multicultural’ to celebrate St George’s Day, England’s version of the 4th of July.
The council said that displaying the English flag may have been seen as “racist” towards immigrants.
Half of Western European men descended from one Bronze Age ‘king’ 2016-04-27 2:09
Half of Western European men are descended from one Bronze Age ‘king’ who sired a dynasty of elite nobles which spread throughout Europe, a new study has shown.
The monarch, who lived around 4,000 years ago, is likely to have been one of the earliest chieftains to take power in the continent.
He was part of a new order which emerged in ...
"Local Residents" Are Filmed Stealing Dozens of Bottles of Water at London Marathon Stop 2016-04-25 23:10
Editor's Comment: "Local" residents? Why bother blurring their faces? We know who they are.
London marathon runners were robbed of dozens of bottled waters when thieves raided a refreshment area armed with trolleys during today's race.
Nearby residents - including parents with children - were captured on camera piling up crates of free water handed out by volunteers during the 26-mile event.