Lifespan link to antidepressant drug
2007 11 26

From: news.bbc.co.uk


Ed Comment: Just pop the pills and a long and happy life awaits you :)
Check the related links for more information on antidepressants.


An antidepressant drug lengthens tiny worms' lives and offers hope of humans living longer too, US scientists say.
In the study, detailed in journal Nature, nematode worms were exposed to 88,000 chemicals in turn and mianserin extended lifespan by almost a third.

The drug seems to mimic the effects on the body of the only known animal long-life regime - virtual starvation.

Experts said the findings might point to there being genes in humans that could be targeted to increase lifespan.

For a little-understood reason, depriving the body of all but the minimum amount of calories needed to survive seems to enhance longevity.

However, this is not a practical solution for most people in the modern world and the team from the Fred Hutchinson Cancer Research Center, in Seattle, believe they may have found an easier way to achieve the same effect.

Ideal subjects
While research using nematode worms might not seem to have much relevance to us, in many key ways they are similar, with a central nervous system and sexual reproduction.

In addition, they live for only a matter of weeks, making them ideal subjects for the study of lifespan.

A vast screening programme found that most chemicals had zero impact on the lifespan of the worms, but the antidepressant drug boosted their lives by an average of 30%.

More interestingly, it may be doing this by mimicking the effects of starvation in the brain.

"We don't have any explanation for this," said Dr Linda Buck, one of the researchers.

"All we can say is that if we give the drug to calorific-restricted animals, it doesn't increase their lifespan any further.

"That suggests the same mechanism may be involved."

Food source
She said that it was possible the drug was disturbing the balance of two brain chemicals which help the nematode decide whether there is enough food around to justify laying eggs.

This, she said, might produce a "perceived, but not real" state of starvation.

Dr Buck said that finding a chemical that increased lifespan in animals might point to genes in humans that could be targeted to do the same.

"It may be possible to identify additional genes important in ageing.

"In addition, the chemical approach could point to drugs suitable for testing in mammals."

Professor Janet Lord, from Birmingham University, and a former chair of the British Society for Ageing Research, said: "What's exciting is that the lifespan extension effects we see extend right across the species, from worms and fruit flies to mammals.

"At the moment, there are interesting experiments in primates which, although the animals involved are only middle-aged so far, suggest that calorific restriction does have an effect on longevity."

Article from: http://news.bbc.co.uk/2/hi/health/7106007.stm



Related Articles
Red Ice Creations Radio - Dr. Ann Blake-Tracy - The Danger of SSRI's (Antidepressants)
SSRI Antidepressants & Homicide As Well As Suicide
Teen Killer's Prozac Increased A Week Before Shooting
Psychiatry and the Schools: Mental Hygiene in the 21 st Century
drugawareness.org
The Mass Poisoning Of Humanity
LSD - The Beyond Within (Video)
New FDA Analysis: Link Between Antidepressants and Suicide
Prozac is linked to child suicide in US


Latest News from our Front Page

James Foley Beheading: What They’re Not Telling You
2014 08 27
The latest poster child for military expansion in the middle east poses a host of disturbing questions. --- Experts: James Foley Beheading Video Likely Fake By Paul Joseph Watson| Infowars Forensic analysis confirms Infowars investigation that footage was staged as war propaganda Confirming Infowars’ analysis on Thursday, British forensic experts have concluded that the ISIS beheading video involving James Foley was in all likelihood ...
US forces move into Syria as Barack Obama paves way for airstrikes on ISIS
2014 08 27
US forces move into Syria: Obama paves way for airstrikes on ISIS after sending in spy planes - despite Assad warning that any attack will be seen as ’aggression’ Barack Obama has paved the way for airstrikes against ISIS targets in Syria after spy planes started operating in the country on his command, according to U.S officials. While the White ...
Stop creating a climate of fear!
2014 08 27
ok. listen up political correct people! if you’re someone who reflexively calls others “racists” or “neofascists” without first checking into whether or not they actually are, you need to STOP it, because you’re creating a climate of fear in which people are afraid to do their jobs. and now i’m not talking about some academics sitting comfortably in their ivy towers, ...
Gov. Jerry Brown to Mexican Illegals: ’You’re All Welcome in California’
2014 08 27
On Monday evening, California Governor Jerry Brown said all Mexicans, including illegal immigrants, are welcome in California. According to the Los Angeles Times, while introducing Mexican President Enrique Peña Nieto, who said America is "the other Mexico," Brown "spoke about the interwoven histories of Mexico and California." He "nodded to the immigrants in the room, saying it didn’t matter if ...
Election Posters in New Sweden
2014 08 27
Swedish prime minister Fredrik Reinfeldt has promised continued mass immigration at the expense of welfare reform and tax cuts. Reinfeldt’s Moderates party consequently does everything in their power to recruit immigrants’ votes. Placards for the forthcoming elections, widely distributed in immigrant-dominated enclaves in Sweden, has Arabic text, the language that now increasingly is dominating major parts of "New Sweden." In the ...
More News »