Placeboís Effect May Depend on Your Genes
Your response to placebos, or dummy medicine, may depend on your genes, according to a new study. People with a gene variant that codes for higher levels of the brain chemical dopamine respond better to placebos than those with the low-dopamine version. The findings, reported online Oct. 23 in the journal PLoS One, could help researchers design medical studies that distinguish the placebo response from the underlying effect of a medicine ó the real aim of drug trials.
ďThis is a possible way to discern who is going to be a placebo responder or nonresponder in a clinical trial,Ē said study co-author Kathryn Hall of Beth Israel Deaconess Medical Center in Brookline, Mass.
People report feeling better after receiving a placebo, such as a sugar pill or fake treatment, for conditions ranging from chronic pain to Parkinsonís disease. But only some patients respond strongly, and thereís no way to predict who will improve on a placebo. A few studies have provided clues. Differences in versions of the catechol-O-methyltransferase (COMT) gene, which determines levels of dopamine in the brainís prefrontal cortex, are linked to differences in reward-seeking and pain perception. People with the high-dopamine version, or allele, of the COMT gene feel pain more acutely and seek rewards more strongly than those who have the low-dopamine copy.
That led the researchers to wonder whether the gene modulates placebo response. To find out, Hall and her colleagues analyzed DNA from 104 patients with irritable bowel syndrome who were randomized to one of three groups: One was told they were on the waiting list for treatment, another received a placebo in the form of seemingly real, curt acupuncture, and the third group received fake acupuncture from a caring, warm practitioner who looked patients in the eye, asked about their progress, and even touched them lightly, Hall told LiveScience.
Patients with the high-dopamine version of the gene felt slightly better after seeing the curt, all-business health-care provider that gave placebo acupuncture. But they were six times as likely to say their symptoms improved with a caring practitioner as those with the low-dopamine gene, who didnít improve much in any group. The findings suggest that medical studies called clinical trials could identify treatment versus placebo effect by grouping patients by gene variant, Hall said. Knowing up front the level of placebo effect for a clinical trial could reduce the cost of the trial significantly by using fewer participants, for instance, she said.
People with the high-dopamine allele of the gene may do well on the placebo with the nurturing treatment because they are generally more attuned to their environments, said University of Michigan psychiatrist Jon-Kar Zubieta, who was not involved in the study.
ďIt speaks about an interaction between the environment and the gene,Ē Zubieta said. ďItís very possible that individuals with this allele are more able to process those positive environmental cues.Ē
Article from: deskarati.com
Tune into Red Ice Radio:
Bruce Lipton - The Biology of Belief
David Crowe - Rethinking AIDS
Anthony Peake & Tom Campbell - Consciousness Creates Reality
Michael Sharp - Consciousness & The Ascension Process
Lloyd Pye - Human Design & Properties of Annunaki Genes
Nick Begich - Hour 1 - Controlling the Human Mind
Dr David Hamilton: Placcebo Effect & Quantum Healing
Dr David Hamilton íThe Science Of Beliefí
Biology of Belief - by Bruce Lipton (Documentary)
Marmosets can meditate (and are immune to the placebo effect)
Placebo Effectís Neural Activity Photographed for First Time
The Placebo Effect - The Triumph of Mind over Body
Latest News from our Front Page
Better Identification of Viking Corpses Reveals: Half of the Warriors Were Female
Shieldmaidens are not a myth! A recent archaeological discovery has shattered the stereotype of exclusively male Viking warriors sailing out to war while their long-suffering wives wait at home with baby Vikings. (We knew it! We always knew it.) Plus, some other findings are challenging that whole ‚Äúrape and pillage‚ÄĚ thing, too.
Researchers at the University of Western Australia decided ...
Off Your Knees, Germany! Ernst Zundel 1983 - 2003
For more information on the holocaust, how the war was forced upon Germany, and the REAL victims of the second world war see:
IRS Drops Attack For Six Years ‚Äď No Evidence of Jurisdiction
A big congrats to a friend I‚Äôve been working with for several years, he stood up to the predators commonly called the ‚ÄúIRS‚ÄĚ and they dropped their attack. Thanks also for providing me with the proof below.
The criminals called the ‚ÄúIRS‚ÄĚ initiated an attack claiming my friend was required to file six tax returns, or explain how he made ...
Into Eternity - Finland's 100,000 Year Massive Underground Spent Nuclear Fuel Program
Into Eternity is a documentary about a deep geological repository for nuclear waste. The concept of long-term underground storage for radioactive waste has been explored since the 1950s. The inner part of the Russian doll-like storage canisters is to be composed of copper. Hence in the case of Onkalo it is tightly linked to experiments on copper corrosion in running ...
SPLC Accuses Oath Keepers of Inciting ‚ÄúArmed Confrontation‚ÄĚ Over Sugar Pine Mine
The Southern Poverty Law Center has accused Oath Keepers of inciting an armed confrontation with BLM authorities over the Sugar Pine Mine dispute in Oregon, despite the fact that the organization has explicitly stated that it is not promoting armed confrontation with the feds.
In an article provocatively posted on the organization‚Äôs ‚ÄėHatewatch‚Äô section entitled Oath Keepers Descend Upon Oregon with ...
|More News » |