Scientists have developed an almost 100 per cent accurate test to detect schizophrenics - by checking their gaze.
Impaired eye movement has long been thought to be associated with schizophrenia.
Now a new study has reported a model of testing which demonstrated 98 per cent accuracy in distinguishing between those with and without schizophrenia.
Using ’simple viewing tests’, researchers at Aberdeen University explored the ability of eye movement tests to sort schizophrenics from healthy people.
People with schizophrenia showed well-documented deficits in the ability to track slow moving objects smoothly with their eyes.
Their eye movements tended to fall behind the moving object and then catch up again using rapid eye movements called ’saccades’.
Schizophrenics also found it more difficult to maintain a steady gaze.
The study was led by Dr Philip Benson and Professor David St Clair and involved a range of eye tests where volunteers were asked to track slow moving objects slowly with their eyes (known as smooth pursuit), inspect a variety of everyday scenes (free viewing) and given instructions to keep a steady gaze on a single unmoving target (fixation tasks).
Their findings could speed up detection of the condition and they are now examining whether the tests can be used for earlier intervention in major mental illness.
Dr Benson said today: ’It has been known for over a hundred years that individuals with psychotic illnesses have a variety of eye movement abnormalities, but until our study, using a novel battery of tests, no one thought the abnormalities were sensitive enough to be used as potential clinical diagnostic biomarkers.
’In smooth pursuit, people with schizophrenia have well-documented deficits in the ability to track slow moving objects smoothly with their eyes. Their eye movements tend to fall behind the moving object and then catch up with the moving object using rapid eye movements called saccades.
’In the free-viewing test, whereas most individuals follow a typical pattern with their gaze as they scan the picture, those with schizophrenia follow an abnormal pattern and in the fixation task individuals with schizophrenia found it more difficult to maintain a steady gaze.’
This graphic shows schizophrenics and those without the condition track objects with their eyes differently.
Several methods were then used to model the data and the accuracy of each of the created algorithms was tested by using eye test data from another group of cases and controls. Combining all the data, one of the models achieved 98 per cent accuracy.
Professor St Clair added: ’We are keen to explore how best our findings can be developed for use in routine clinical practice.
’Typical neuropsychological assessments are time-consuming, expensive, and require highly trained individuals to administer. In comparison, these eye tests are simple, cheap, and take only minutes to conduct.
’This means that a predictive model with such precision could potentially be incorporated in clinics and hospitals to aid physicians by augmenting traditional symptom-based diagnostic criteria.
’The next thing we want to know is when the abnormalities are first detectable and can they be used as disease markers for early intervention studies in major mental illness?’
The study has been published in the November issue of the academic journal Biological Psychiatry.
The journal’s editor Dr. John Krystal commented: ’It is encouraging to see the high sensitivity of this model for the diagnosis of schizophrenia. It will be interesting to see the extent to which this approach enables clinical investigators to distinguish people with schizophrenia from individuals with other psychiatric disorders.’
Illegal Aliens Cleared For U.S. Military Service 2014 10 18
The Pentagon announced a new policy allowing illegal immigrants the opportunity to enlist in the armed forces, Thursday.
USA Today reports that the new recruitment policies will focus on people with "high-demand skills" like foreign language acumen and health care training:
"For the first time, the program — known as Military Accessions in the National Interest, or MAVNI — will ...
Bronze Age Sundial-Moondial Discovered in Russia 2014 10 16
A strange slab of rock discovered in Russia more than 20 years ago appears to be a combination sundial and moondial from the Bronze Age, a new study finds.
The slab is marked with round divots arranged in a circle, and an astronomical analysis suggests that these markings coincide with heavenly events, including sunrises and moonrises.
The sundial might be "evidence of ...
Humans may only survive 68 days on Mars 2014 10 15
Space enthusiasts planning a move to Mars may have to wait to relocate: conditions on the Red Planet are such that humans would likely begin dying within 68 days, a new study says.
Oxygen levels would start to deplete after about two months and scientists said new technologies are required before humans can permanently settle on Mars, according to the study ...
Tom Sunic’s letter to the US Ambassador to Hungary 2014 10 14 October 11, 2014
Mr. André Goodfriend
Embassy of the United States of America
Szabadság tér 12
Dear Mr. Goodfriend,
As an American citizen I would hereby like to express my concern over the recent decision by the Hungarian government to ban the National Policy Institute (NPI) conference which had been scheduled to take place in Budapest from October 3 to October 5, 2014. ...
"Vampire grave" found in Bulgaria 2014 10 14
A "vampire grave" containing a skeleton with a stake driven through its chest has been unearthed by a man known as "Bulgaria’s Indiana Jones".
Professor Nikolai Ovcharov – a crusading archaeologist who has dedicated his life to unearthing mysteries of ancient civilisations – said that he had made the discovery while excavating the ruins of Perperikon, an ancient Thracian city ...