On average, the residents of Sun City, Arizona, occupy their domiciles for a dozen years. When they depart—almost always by dying—they often leave their brains behind. The stages of physical and mental decline take them from their dream house to a hospital off Del Webb Boulevard, then to a nursing home, and finally back to the medical complex, where researchers harvest their most important organ. Hoping to do good for science, they have enrolled in the Brain and Body Donation Program of the Banner Sun Health Research Institute—widely considered the world’s preeminent brain bank.
A large base of well-
documented donors in close proximity sets the Sun City program apart from other repositories, which often have scant information about patients who may be scattered and diverse. Here, healthy, active seniors who eventually die of, say, heart disease, can be compared with others who develop neurodegenerative disorders. Because the two sets of subjects have similar backgrounds, lifestyles, and ethnic traits, changes relating to a brain disease should be easier to detect.
The institute is also famed for its crack autopsy team, which responds so quickly that no more than three hours elapse from the time a donor expires to the time that the brain is removed and preserved. “We’re not the biggest brain bank in the world, but we have the highest-quality tissue,” says pathologist Thomas Beach, the program director, who notes that donors must live within a 50-mile radius of the morgue.
After withdrawing some blood and cerebrospinal fluid for analysis, a team of rotating techs on duty 24 hours a day remove the top of the skull and take out the brain. The next step relies on a device that resembles a bread slicer, which is used to cut the brain into sections one centimeter thick. The slices from the left side are fixed in formaldehyde and those from the right are frozen between sheets of dry ice. Part of the tissue from the formaldehyde sections is stained, pressed into slides, and put under the microscope to verify the brain’s condition, healthy or diseased. The rest, light brown and convoluted, may be held in Tupperware containers at the research institute indefinitely. A recent visit to the storeroom turned up a container dated 1994.
These fresh brain sections, kept in carefully monitored freezers, are hot properties for advanced neuroscience research. Because the brain’s proteins, DNA, and other molecules are still intact, pharmaceutical companies are willing to pay high prices for the tissue.
One of the most prized specimens is a sample of the entorhinal cortex, regarded as the X on the brain’s treasure map by Alzheimer’s researchers because the disease is thought to originate there; the nonprofit brain bank charges up to $1,000 for half a gram.
Prehistoric Underwater Wall Divides Scientists 2013 12 11 Two camps of scientists have faced off on the issue of the underwater structure known as Bimini Road off the coast of the Bahamas since it was first discovered in 1968.
One camp says it is a 12,000–19,000-year-old man-made structure—flouting the conventional understanding that advanced civilizations only emerged some 5,000 years ago.
The other camp says it is a natural formation.
Author, Researcher Lloyd Pye Dies 2013 12 10 We’re grieved by the sad news that writer and researcher Lloyd Anthony Pye passed away yesterday, December 9, 2013, after a battle with cancer. He was best known for his work with The Starchild Project.
Lloyd was a frequent welcome guest to Red Ice Radio, and we enjoyed the opportunity to speak with him about his work and his writing over ...
Mars May Have Harbored Life 3.6 Billion Years Ago 2013 12 10 Mudstones from Gale Crater, the original landing site of Curiosity, were formed in a lake which may have existed on the planet for hundreds of thousand of years according to scientists.The basin which is 150km wide with a mountain at its centre, could very well have sustained more than one lake approximately 3.6 billion years ago.
Research analysis shows that the ...
Geologists discover ’super volcano’ in Utah, possibly larger than Yellowstone 2013 12 10 Geologists at Brigham Young University have discovered what may be the world’s largest "super" volcano that erupted in Utah’s own backyard.
While there are a variety of volcanoes that blast away in different ways, super volcanic eruptions are the biggest that collapse into large calderas. Yellowstone Park is the remains of one of those calderas and it’s still very much alive ...
Rice grown near crippled Fukushima nuclear plant served to govt officials 2013 12 10 Rice from fields in the Fukushima prefecture, evacuated after the worst nuclear disaster in Japan, will be served to government officials for 9 days in a bid to demonstrate the safety of the country’s most-beloved crop, a local broadcaster reported.
The rice cultivated in several decontaminated fields in the Yamakiya District in Kawamata Town and Iitate Village, two areas designated as ...