They beat like real heart cells, but the rat cardiomyocytes in a dish at Harvard University are different in one crucial way. Snaking through them are wires and transistors that spy on each cell’s electrical impulses. In future, the wires might control their behaviour too.
Versions of this souped-up, "cyborg" tissue have been created for neurons, muscle and blood vessels. They could be used to test drugsMovie Camera or as the basis for more biological versions of existing implants such as pacemakers. If signals can also be sent to the cells, cyborg tissue could be used in prosthetics or to create tiny robots.
"It allows one to effectively blur the boundary between electronic, inorganic systems and organic, biological ones," says Charles Lieber, who leads the team behind the cyborg tissue.
Artificial tissue can already be grown on three-dimensional scaffolds made of biological materials that are not electrically active. And electrical components have been added to cultured tissue before, but not integrated into its structure, so they were only able to glean information from the surface.
Bio-scaffolds go electric
Bioengineers at Harvard University have created the first examples of cyborg tissue: Neurons, heart cells, muscle, and blood vessels that are interwoven by nanowires and transistors. Source
Lieber’s team combined these strands of work to create electrically active scaffolds. They created 3D networks of conductive nanowires studded with silicon sensors. Crucially, the wires had to be flexible and extremely small, to avoid impeding the growth of tissue. The scaffold also contained traditional biological materials such as collagen.
The researchers were able to grow rat neurons, heart cells and muscle in these hybrid meshes. In the case of the heart cells, they started to contract just like normal cells, and the researchers used the network to read out the rate of the beats.
When they added a drug that stimulates heart cell contraction, they detected an increase in the rate, indicating the tissue was behaving like normal and that the network could sense such changes.
Lieber’s team also managed to grow an entire blood vessel about 1.5 centimetres long from human cells, with wires snaking through it. By recording electrical signals from inside and outside the vessel– something that was never possible before– the team was able to detect electrical patterns that they say could give clues to inflammation, whether tissue has undergone changes that make it prone to tumour formation or suggest impending heart disease.
Nigel Farage (UKIP) Speech on the EU, UK & Mass Immigration 2014 03 08
UKIP Nigel Farage Spring Conference speech - 2014
Red Ice Radio:
Nigel Farage MEP - The State of the EU & The Undemocratic Treaty of Lisbon
Labour wins UK by-election as Ukip trumps Tories
The ruling coalition in the UK was dealt a blow in the latest by-election test, as the UK Independence party pushed the Conservatives and Liberal Democrats into third and fourth ...
Pentagon studying Putin’s body language to predict his behavior 2014 03 07
The Pentagon has spent hundreds of thousands of dollars in recent years so that researchers can study the body movements of foreign leaders, including Russian President Vladimir Putin, in hopes of predicting future behavior.
An article published by USA Today reporter Ray Locker on Thursday and corroborated by documents discovered by RT provides rare insight into a scarcely-discussed military effort that ...
Pentagon Claims That Climate Change ‘Enables Terrorism’ 2014 03 07 In it’s latest Quadrennial Defense Review the Pentagon has said that climate change and ’erratic’ climate will cause increased terrorist activity.
The four yearly reports highlight threats that face civilization and this years homed in on climate change causing an increase in terrorism.
It also mentioned that rises in sea levels and other issues associated with a warming planet will lead ...
Scientists Control Tiny Mechanical Probes Inside Human Cells 2014 03 07 Nanotechnology doesn’t get as much attention these days as genetic and stem cell approaches to medicine, but all three aim to target the causes of illness with greater precision and less collateral damage in the rest of the body than conventional approaches.
Nanotech breakthroughs have come more slowly than many had hoped, but a recent success shows progress toward the goal ...
Fukushima: The Ticking Nuclear Bomb. Over 800 Tons of Radioactive Material Pouring into Pacific Ocean 2014 03 07
First published by GR in October 2013
In August this column ran a piece claiming that the Pacific Ocean was being poisoned by radioactive material escaping from Fukushima, two years after the devastating tsunami and meltdown at the Japanese nuclear facility. Three months later, shocking evidence points towards a calamity situation.
Silence from the corporate media.
There is growing evidence coming from ...