Scientists grow sperm in a lab
2011 03 28

By Ian Sample | Guardian.co.uk


Mouse sperm were grown using a technique that could also help preserve the fertility of boys undergoing cancer treatment.

Scientists have grown sperm in the laboratory in a landmark study that could help preserve the fertility of cancer patients and shed fresh light on male reproductive problems.

Fertility experts called the work a "crucial experimental advance" towards the use of lab-grown sperm in the clinic and a stepping stone to the routine creation of human sperm for men who cannot make the cells normally.

Though the procedure would be illegal in Britain under current legislation, sperm grown in the laboratory, if proven safe, could be used to help infertile men have children through standard IVF treatments.

The procedure could also benefit boys with cancer who are too young to produce sperm but are at risk of being made infertile by radio- or chemotherapy.

While men can have their sperm frozen before cancer treatment, the latest research suggests boys could have testicular tissue removed and kept in cold storage for use in later life.

Japanese researchers cultivated small pieces of tissue from the testes of baby mice on a gel bathed in nutrients. After several weeks they collected viable sperm from the tissue.

Scientists Grow Sperm in Lab


Video from: YouTube.com

The sperm appeared to be completely healthy and were used in IVF treatments to produce 12 live mouse pups that went on to have young of their own. Seven of the mice were born after sperm heads were transferred into 23 eggs using a technique called round spermatid injection, and another five were born after 35 eggs were fertilised using intracytoplasmic sperm injection (Icsi), a common IVF procedure.

Importantly, the scientists retrieved healthy sperm from tissue that was cultivated after being frozen for up to 25 days, suggesting that cold storage did not harm the cells. The work, reported in the journal, Nature, is the most successful attempt yet to grow mammalian sperm from testicular tissue in the laboratory.

"One of the problems I face, as a urologist, is that we do not have any effective ways to treat patients suffering from male infertility due to defective or insufficient sperm production," said Takehiko Ogawa, who led the study at Yokohama City University Graduate School of Medicine. "Most of these problems are for unknown reasons."

Using the technique, he said, scientists will be able to study the process of sperm production in detail and help elucidate the glitches that cause infertility.

In an accompanying article, Marco Seandel and Shahin Rafii at the Weil Cornell Medical College in New York said the work was "a crucial experimental advance along the thorny path to the clinical use of sperm" grown in the lab. They warn, however, that the fertility of mouse pups born from the lab-grown sperm was a "crude indicator" of their health, and that subtle genetic changes in the sperm "could be pivotal for the wellbeing of subsequent generations".

Allan Pacey, a senior lecturer in andrology at Sheffield University, said: "It is not totally clear how sperm are formed and why in some men it doesn’t work properly. This could help discover new drugs or treatments to stimulate infertile men to produce more or better sperm. It also may help preserve the fertility of some males."

The study, he said, was "a small but important step in understanding how sperm are formed which may, in time, lead to us being able to routinely grow human sperm in the laboratory."

"It is clearly important to make sure that any sperm produced are safe and give rise to healthy offspring when used, and that they in turn have healthy offspring. We need to be cautious with this kind of work," he added.



Article from: guardian.co.uk




Eugenics - Human Sperm Created in British Lab (2009)

Eugenics - Human Sperm Created in British Lab (Embryonic Stem Cells)

Video from: YouTube.com






Related Articles
US clinic offers British couples the chance to choose the sex of their child
Hybrid embryos could be created within months
Baby Born From 20-Year-Old Frozen Embryo
Dating Website for ’Beautiful People’ Aims at "Noble Cause" Designer Babies
The Disappearing Male (Video)
Young women are freezing their fat so they can use it to firm and boost their bodies 30 years later
British fertility clinic raffling human egg
Woman offered ’£200 to be sterilized’


Latest News from our Front Page

The Aeon of Horus is Ending and the Elites are Nervous as their Icons are Dying
2014 04 18
I predict there is going to be a huge resurgence of interest in European indigenous spiritual traditions from Norse to Celtic/Gaelic to Slavic and so on. Millions of Europeans are going to realise that we are the victims of Christianity and New Age garbage. Their bastardised Kabbalah, the psychic force used by Crowley and the elites to cement his Aeon ...
Easter - Christian or Pagan?
2014 04 18
From: truthbeknown.com Contrary to popular belief, Easter does not represent the "historical" crucifixion and resurrection of Jesus Christ. In reality, the gospel tale reflects the annual "crossification" of the sun through the vernal equinox (Spring), at which time the sun is "resurrected," as the day begins to become longer than the night. Rather than being a "Christian" holiday, Easter celebrations date back ...
Man-Made Blood Might Be Used in Transfusions by 2016
2014 04 18
Researchers in the U.K. have created the first man-made red blood cells of high enough quality to be introduced into the human body The premise of the HBO show and book series True Blood revolves around a technological breakthrough: scientists figure out how to synthesize artificial human blood, which, as an ample new source of non-human food, allows vampires to "come ...
The Trials of the Cherokee Were Reflected In Their Skulls
2014 04 18
Researchers from North Carolina State University and the University of Tennessee have found that environmental stressors – from the Trail of Tears to the Civil War – led to significant changes in the shape of skulls in the eastern and western bands of the Cherokee people. The findings highlight the role of environmental factors in shaping our physical characteristics. ...
Our Fears May Be Shaped by Ancestral Trauma
2014 04 18
Last December, an unsettling Nature Neuroscience study found that mice who were taught to associate the smell of cherry blossoms with pain produced offspring who feared the smell of cherry blossoms, even if they had never been exposed to it before. We knew that the process was epigenetic—that it was not hard-wired in the permanent genetic structure of the mouse—but ...
More News »