First genome transplant turns one species into another
2007 07 01

By Ian Sample | guardian.co.uk


Research is aimed at producing green fuel. Critics warn of terrorists creating new bioweapons.

Scientists have converted an organism into an entirely different species by performing the world's first genome transplant, a breakthrough that paves the way for the creation of synthetic forms of life.
The team, led by Craig Venter, the man who raced to sequence the human genome, wants to build new microbes to produce environmentally friendly fuels.

The group's study, details of which were revealed in the US journal Science yesterday, proves it is possible to transplant a complete set of genetic instructions into an organism, in effect turning it into the same species the DNA was taken from.

The proof of principle experiment solves the first of two big difficulties which have hindered the creation of artificial life. The team, based at Dr Venter's not-for-profit institute in Rockville, Maryland, now hopes to overcome the second hurdle, by designing new genetic codes on computers and transplanting them into organisms to produce new life forms.

The team is focusing on creating micro-organisms which produce green fuels as natural waste products. "One of the goals we have is trying to see if we could design cells to manufacture new types of fuel to break our dependency on oil and coal and try to do something about carbon dioxide," Dr Venter said. "We look forward to trying to have the first fuels from genetically modified and even synthetic organisms, certainly within the decade."

The work is at the cutting edge of synthetic biology, which is rapidly becoming one of the most contentious fields in science. Researchers have developed the tools to recreate the devastating 1918 flu virus, and are working on ways to genetically modify human cells and understand the most fundamental mechanisms of life.

But critics fear the field is progressing too fast for society to grasp. Some are concerned that artificial organisms could escape and damage the environment, or that maverick scientists or terrorist groups could create powerful new bioweapons.

Dr Venter's team commissioned an 18-month study into the bioethics of their research, which gave strong approval but echoed concerns about the dangers.

In the experiment, researchers extracted the whole genetic code from a simple bacterium, Mycoplasma mycoides. They squirted the DNA into a test tube containing a related species, Mycoplasma capricolum. They found that some of the bacteria absorbed the new genome and ditched their own. These microbes grew and behaved exactly like the donor.

Article from: http://www.guardian.co.uk/science/story/0%2C%2C2114428%2C00.html



Related Articles
Patent sought on 'synthetic life'
Why Embryonic Stem Cell Research? It's About Human Engineering, Not Ending Disease


Latest News from our Front Page

Secret underground tunnels of ancient Mesopotamian cult revealed under Ani ruins
2014 09 01
For the first time in history, the academic world is paying attention to the spectacular underground world of Ani, a 5,000-year-old Armenian city located on the Turkish-Armenian border. Hurriyet Daily News reports that scientists, academics, and researchers have just met at a symposium in Kars titled ‘Underground Secrets of Ani’ to discuss the city’s underground world mentioned in ancient ...
A Government Vision Of The Future That Isn’t That Great
2014 09 01
Here’s a report by the UK Ministry of Defense, a document that they’re not hiding - it’s not classified. In fact, they WANT you to read it: the Global Strategic Trends 2045. For your convenience, they’ve even produced a handy video about their dire predictions: They present a warning call for how things are going to be bad in the future. ...
Bad Memories Turned to Happy Ones in Mice Brains
2014 09 01
Memories are often associated with emotions, and these feelings can change through new experiences and over time. Now, using light, scientists have been able to manipulate mice brain cells and turn the animals’ fearful memories into happy ones, according to a new study. Memories are encoded in groups of neurons that are activated together or in specific patterns, but it is ...
CIA MKULTRA: they intended to use drugs for “everything”
2014 09 01
Drugs to transform individuals…and even, by implication, society. Drug research going far beyond the usual brief descriptions of MKULTRA. The intention is there, in the record. A CIA document was included in the transcript of the 1977 US Senate Hearings on MKULTRA, the CIA’s mind-control program. The document is found in Appendix C, starting on page 166. It’s simply labeled “Draft,” dated 5 May ...
Harmful Compound Found in Many BPA-Free Bottles
2014 09 01
A chemical found in many products labeled “BPA free” may produce many of the same health problems as the original chemical, including hyperactivity and cardiac arrhythmia, according to a pair of studies presented recently at the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago. “BPS, termed the safe alternative to BPA, may be equally as ...
More News »