Researchers may remake Neanderthal DNA
2007 06 27

By Randolph E. Schmid | news.yahoo.com


Researchers studying Neanderthal DNA say it should be possible to construct a complete genome of the ancient hominid despite the degradation of the DNA over time.

There is also hope for reconstructing the genome of the mammoth and cave bear, according to a research team led by Svante Paabo of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.

Their findings are published in this week's online edition of Proceedings of the National Academy of Sciences.

Debate has raged for years about whether there is any relationship between Neanderthals and modern humans. Some researchers believe that Neanderthals were simply replaced by early modern humans, while others argue the two groups may have interbred.

Sequencing the genome of Neanderthals, who lived in Europe until about 30,000 years ago, could shed some light on that question.

In studies of Neanderthals, cave bear and mammoth, a majority of the DNA recovered was that of microorganisms that colonized the tissues after death, the researchers said.

But they were able to identify some DNA from the original animal, and Paabo and his colleagues were able to determine how it broke down over time. They also developed procedures to prevent contamination by the DNA of humans working with the material.

"We are confident that it will be technically feasible to achieve a reliable Neanderthal genome sequence," Paabo and his researchers reported.

They said problem of damaged areas in some DNA could be overcome by using a sufficient amount of Neanderthal DNA from different individuals, so the whole genome can be determined.

"The contamination and degradation of DNA has been a serious issue for the last 10 years," observed Erik Trinkaus, a professor at Washington University in St. Louis. "This is a serious attempt to deal with that issue and that's welcome."

"I'm not sure they have completely solved the problem, but they've made a big step in that direction," said Trinkaus, who was not involved in the research.

Anthropologist Richard Potts of the Smithsonian's National Museum of Natural History, called the work "a very significant technical study of DNA decay."

The researchers "have tried to answer important questions about the potential to sequence ancient DNA," said Potts, who was not part of the research.

Milford Wolpoff, a University of Michigan Anthropologist, said creating a complete Neanderthal genome is a great goal.

But it is "sample intensive," he said, and he isn't sure enough DNA is available to complete the work. Curators don't like to see their specimens ground up, he said.

The research was funded by the Max Planck Society and the National Institutes of Health.

Article from: http://news.yahoo.com/s/ap/20070625/
ap_on_sc/neanderthal_dna



Related Articles
History Of Humans Unravels As Scholar Exposed As Fraud
Subtle Bodies - Manipulating the Mind of Man
The Hermetic Universe


Latest News from our Front Page

Obama critic D’ouza spared prison for violating election law
2014 09 24
Conservative author and filmmaker Dinesh D’Souza avoided prison on Tuesday when a U.S. judge sentenced him to serve eight months in a community confinement center after he pleaded guilty to violating campaign finance law. D’Souza, 53, was ordered by U.S. District Judge Richard Berman in Manhattan to live in a center, which would allow him to leave during non-residential hours for ...
’Digital twins’ will make decisions for us - and even console loved ones after we die by 2020, futurist claims
2014 09 23
By 2020, our day-to-day lives, relationships and even what to have for dinner could be controlled and run by digital versions of ourselves. According to futurist John Smart, within the next six years many of us could have so-called ‘digital twins’ that schedule our appointments and even have conversations with others on our behalf. And they could one day console loved ones ...
Israel Joins The Fighting, Shoots Down Syrian Warplane Which Acted In "Threatening Manner"
2014 09 23
Whether as a result of recent icy to quite icy diplomatic relations between the two nations, or just because it has other motives, Israel had clearly abstained from joining the US effort to contain the CIA-created ISIS terrorist juggernaut. However, overnight, with the US finally doing what Israel has hoped it would do for so long, namely being engaged in ...
Proof Ebola Is Airborne And U.S. Troops Will Be Caught In A Death Trap
2014 09 23
“Help needs to come fast. Because even if the new U.S. aid starts to slow down the epidemic next week, it will take a year or a year and a half to wipe out Ebola from West Africa,” says Jeffrey Shaman, an associate professor of environmental health sciences at Columbia University’s Mailman School of Public Health. He’s making models of ...
Your Smartphone Broadcasts Your Entire Life To The Secret Service
2014 09 23
Intelligence services collect metadata on the communication of all citizens. Politicians would have us believe that this data doesn’t say all that much. A reader of De Correspondent put this to the test and demonstrated otherwise: metadata reveals a lot more about your life than you think. Ton Siedsma is nervous. He made the decision weeks ago, but keeps postponing it. ...
More News »